Receptor
PDB id Resolution Class Description Source Keywords
1GNR 1.85 Å EC: 3.6.5.2 X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND M ANT DGPPNHP HOMO SAPIENS GTP BINDING PROTEIN
Ref.: X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP. J.MOL.BIOL. V. 253 132 1995
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CAG A:167;
Valid;
none;
submit data
672.327 C18 H23 N6 O16 P3 C[C@H...
MG A:168;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1CLU 1.7 Å EC: 3.6.5.2 H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GT HOMO SAPIENS GTP HYDROLASE SIGNAL TRANSDUCTION CANCER G-DOMAIN HYDROL
Ref.: GUANOSINE TRIPHOSPHATASE STIMULATION OF ONCOGENIC R MUTANTS. PROC.NATL.ACAD.SCI.USA V. 96 7065 1999
Members (192)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 6GOD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 6BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3RS3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 2CL6 - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
5 5WDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 6ARK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 6P8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 5VPZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 6MBQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
16 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 6F76 - CVK C24 H26 N2 O3 CN(C)Cc1cc....
18 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
19 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
20 6E6G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 4WA7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
22 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
24 5OCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
25 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
26 6P8X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
27 4XVQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
28 5V71 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
29 5VP7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
30 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
31 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
32 6GJ7 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
33 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
34 5VBM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
35 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
36 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
39 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
40 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 6E6C - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
43 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
44 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
45 6PGP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
46 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
47 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
48 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
49 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
51 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
52 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
53 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
54 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
55 6M9W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
56 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
57 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
58 5VQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
59 5V9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
60 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
61 4TQA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 6GOF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
63 6GOM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
64 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
65 5VPY - 9GM C10 H17 N6 O13 P3 c1nc2c(n1[....
66 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
67 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
68 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
69 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
71 6E6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
72 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
73 5VQ6 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
74 6DZH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
75 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
76 5V6V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
77 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
78 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
80 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
81 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
82 6P8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
83 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
84 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
85 6QUW - JJQ C14 H20 N2 C[C@@]12CC....
86 5V6S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
87 5UK9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
88 6ASE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
89 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
90 6PGO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 5B30 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
92 5B2Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
93 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
94 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
95 6P8W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
96 5VQ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
97 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
98 5VPI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
99 5W22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 6GJ6 Kd = 20.4 uM EZZ C19 H19 N3 O2 CN(C)Cc1c(....
101 6MQN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
102 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
103 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
104 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
105 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
106 6QUX Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
107 6GJ8 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
108 6BP1 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
109 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
110 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
111 6GJ5 Kd = 440 uM F0N C20 H19 N3 O c1ccc2c(c1....
112 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
113 5VBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
114 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
115 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
116 5UHV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
117 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
118 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
119 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
120 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
121 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
122 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
123 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
124 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
125 5VQ8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
126 6MBT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
127 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
128 6B0Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
129 6GQT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
130 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
131 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
132 5WDP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
133 6QUU - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
134 6GOE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
135 4TQ9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
136 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
137 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
138 5OCT - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
139 5VBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
140 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
141 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
142 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
143 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
144 6GOG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
145 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
146 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
147 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
148 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
150 4QL3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
151 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
152 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
153 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
154 5OCG - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
155 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 6QUV Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
157 6B0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
158 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
159 6OIM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
160 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
161 5WDQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
164 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
165 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
166 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
167 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
168 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
170 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
171 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
172 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
173 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
174 5VQ2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
175 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
176 4XVR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
178 5F2E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
179 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
180 6MQG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
181 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 6P0Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
183 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
184 5WHD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
185 6CU6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
186 5V9O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
187 5V9U - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
188 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
189 6E6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
190 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
191 6MBU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
192 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
70% Homology Family (208)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 6GOD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 6BOF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3RS3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 2CL6 - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
5 5WDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 6ARK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 6P8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 5VPZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 6MBQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
16 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 6F76 - CVK C24 H26 N2 O3 CN(C)Cc1cc....
18 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
19 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
20 6E6G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 4WA7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
22 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
24 5OCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
25 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
26 6P8X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
27 4XVQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
28 5V71 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
29 5VP7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
30 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
31 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
32 6GJ7 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
33 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
34 5VBM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
35 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
36 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
39 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
40 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 6E6C - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
43 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
44 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
45 6PGP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
46 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
47 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
48 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
49 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
51 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
52 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
53 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
54 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
55 6M9W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
56 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
57 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
58 5VQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
59 5V9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
60 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
61 4TQA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 6GOF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
63 6GOM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
64 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
65 5VPY - 9GM C10 H17 N6 O13 P3 c1nc2c(n1[....
66 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
67 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
68 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
69 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
71 6E6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
72 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
73 5VQ6 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
74 6DZH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
75 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
76 5V6V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
77 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
78 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
80 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
81 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
82 6P8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
83 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
84 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
85 6QUW - JJQ C14 H20 N2 C[C@@]12CC....
86 5V6S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
87 5UK9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
88 6ASE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
89 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
90 6PGO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 5B30 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
92 5B2Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
93 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
94 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
95 6P8W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
96 5VQ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
97 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
98 5VPI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
99 5W22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 6GJ6 Kd = 20.4 uM EZZ C19 H19 N3 O2 CN(C)Cc1c(....
101 6MQN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
102 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
103 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
104 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
105 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
106 6QUX Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
107 6GJ8 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
108 6BP1 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
109 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
110 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
111 6GJ5 Kd = 440 uM F0N C20 H19 N3 O c1ccc2c(c1....
112 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
113 5VBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
114 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
115 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
116 5UHV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
117 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
118 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
119 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
120 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
121 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
122 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
123 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
124 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
125 5VQ8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
126 6MBT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
127 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
128 6B0Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
129 6GQT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
130 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
131 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
132 5WDP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
133 6QUU - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
134 6GOE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
135 4TQ9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
136 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
137 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
138 5OCT - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
139 5VBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
140 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
141 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
142 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
143 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
144 6GOG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
145 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
146 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
147 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
148 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
150 4QL3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
151 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
152 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
153 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
154 5OCG - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
155 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 6QUV Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
157 6B0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
158 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
159 6OIM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
160 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
161 5WDQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
164 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
165 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
166 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
167 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
168 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
170 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
171 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
172 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
173 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
174 5VQ2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
175 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
176 4XVR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
178 5F2E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
179 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
180 6MQG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
181 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 6P0Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
183 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
184 5WHD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
185 6CU6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
186 5V9O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
187 5V9U - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
188 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
189 6E6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
190 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
191 6MBU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
192 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
193 5US4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
194 5UQW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
195 5USJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
196 1KAO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
197 3RAP - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
198 1X1R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
199 1X1S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
200 3X1Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
201 3X1Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
202 3X1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
203 3X1X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
204 1U8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
205 1U90 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
206 1U8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
207 5WDR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
208 5WDS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (311)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 157 families.
1 1Z2A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1Z22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1YZT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1YZU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 1Z08 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 1Z0I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4DKX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 5WDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 6ARK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 6P8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
16 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 5VPZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
18 6MBQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
19 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
20 6F76 - CVK C24 H26 N2 O3 CN(C)Cc1cc....
21 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
22 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 6E6G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
24 4WA7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
25 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
26 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
27 5OCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
28 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
29 6P8X - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
30 4XVQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
31 5V71 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
32 5VP7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
33 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
34 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
35 6GJ7 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
36 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 5VBM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
39 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
40 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
43 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
44 6E6C - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
45 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
46 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
47 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
48 6PGP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
49 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
51 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
52 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
53 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
54 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
55 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
56 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
57 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
58 6M9W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
59 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
60 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
61 5VQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 5V9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
63 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
64 4TQA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
65 6GOF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
66 6GOM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
67 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
68 5VPY - 9GM C10 H17 N6 O13 P3 c1nc2c(n1[....
69 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
71 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
72 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
73 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
74 6E6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
75 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
76 5VQ6 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
77 6DZH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
78 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 5V6V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
80 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
81 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
82 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
83 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
84 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
85 6P8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
86 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
87 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
88 6QUW - JJQ C14 H20 N2 C[C@@]12CC....
89 5V6S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
90 5UK9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 6ASE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
92 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
93 6PGO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
94 5B30 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
95 5B2Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
96 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
97 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
98 6P8W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
99 5VQ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
101 5VPI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
102 5W22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
103 6GJ6 Kd = 20.4 uM EZZ C19 H19 N3 O2 CN(C)Cc1c(....
104 6MQN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
105 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
106 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
107 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
108 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
109 6QUX Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
110 6GJ8 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
111 6BP1 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
112 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
113 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
114 6GJ5 Kd = 440 uM F0N C20 H19 N3 O c1ccc2c(c1....
115 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
116 5VBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
117 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
118 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
119 5UHV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
120 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
121 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
122 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
123 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
124 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
125 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
126 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
127 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
128 5VQ8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
129 6MBT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
130 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
131 6B0Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
132 6GQT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
133 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
134 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
135 5WDP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
136 6QUU - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
137 6GOE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
138 4TQ9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
139 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
140 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
141 5OCT - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
142 5VBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
143 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
144 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
145 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
146 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
147 6GOG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
148 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
150 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
151 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
152 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
153 4QL3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
154 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
155 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
157 5OCG - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
158 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
159 6QUV Kd = 1 mM JJN C22 H25 N3 O CC1(CCN(CC....
160 6B0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
161 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 6OIM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
164 5WDQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
165 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
166 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
167 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
168 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
170 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
171 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
172 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
173 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
174 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
175 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
176 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
177 5VQ2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
178 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
179 4XVR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
180 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
181 5F2E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
183 6MQG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
184 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
185 6P0Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
186 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
187 5WHD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
188 6CU6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
189 5V9O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
190 5V9U - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
191 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
192 6E6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
193 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
194 6MBU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
195 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
196 2Y8E - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
197 2A5J - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
198 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
199 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
200 2P2L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
201 2W2V - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
202 1MH1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
203 2WKP - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
204 2WKR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
205 2WKQ - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
206 1YU9 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
207 2BME - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
208 2BMD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
209 1YZN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
210 3RWM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
211 3RWO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
212 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
213 2F9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
214 2F9M - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
215 1YZK - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
216 1OIV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
217 2FE4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
218 2FFQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
219 2E9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
220 5US4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
221 5UQW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
222 5USJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
223 3NKV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
224 1HUQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
225 1Z07 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
226 1N6R - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
227 1Z0D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
228 1N6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
229 1N6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
230 1N6K - GDP AF3 n/a n/a
231 1N6N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
232 1N6I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
233 1R2Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
234 1N6L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
235 1N6O - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
236 1TU4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
237 6HXU - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
238 1EK0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
239 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
240 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
241 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
242 1D5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
243 1Z0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
244 3E5H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
245 1KAO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
246 3RAP - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
247 1YZQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
248 2GIL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
249 6HH2 Kd = 2.7 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
250 1Z0A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
251 1KY2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
252 1KY3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
253 2HT6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
254 3KKO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
255 3KKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
256 3KKP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
257 1X1R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
258 1X1S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
259 1T91 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
260 1VG8 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
261 2GCP - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
262 2GCN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
263 3X1Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
264 3X1Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
265 3X1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
266 3X1X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
267 4Z8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
268 1G17 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
269 1G16 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
270 1M7B - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
271 2DPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
272 3Q7Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
273 3Q7P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
274 3Q72 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
275 1U8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
276 1U90 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
277 1U8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
278 1YVD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
279 5WDR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
280 5WDS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
281 1Z06 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
282 3TH5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
283 3SBD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
284 1OIX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
285 1OIW - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
286 2QRZ - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
287 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
288 1KMQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
289 1DPF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
290 1FTN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
291 5A0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
292 1A2B - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
293 4U5X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
294 6FF8 Kd = 1.2 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
295 3Q85 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
296 1RYH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
297 1RYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
298 1VG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
299 5XC5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
300 5XC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
301 3RAB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
302 6HDU Kd = 1.2 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
303 1GWN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
304 2EW1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
305 4O25 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
306 4O2R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
307 4O2L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
308 6BSX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
309 5YXH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
310 1XTQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
311 3SEA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CAG; Similar ligands found: 87
No: Ligand ECFP6 Tc MDL keys Tc
1 CAG 1 1
2 GP3 0.682692 0.904762
3 GTP 0.642202 0.880952
4 GSP 0.630631 0.840909
5 GDP 0.62963 0.880952
6 GNH 0.609091 0.892857
7 G1R 0.607143 0.870588
8 9GM 0.60177 0.904762
9 GNP 0.60177 0.904762
10 GTG 0.6 0.917647
11 G3A 0.595041 0.904762
12 GCP 0.59292 0.860465
13 G5P 0.590164 0.904762
14 GFB 0.586777 0.894118
15 GDR 0.586777 0.894118
16 GMV 0.584071 0.860465
17 G 0.583333 0.869048
18 5GP 0.583333 0.869048
19 G2R 0.576271 0.850575
20 GDD 0.565574 0.872093
21 Y9Z 0.565574 0.824176
22 GKE 0.565574 0.872093
23 GDC 0.565574 0.872093
24 JB2 0.56 0.894118
25 6CK 0.556452 0.852273
26 GDX 0.555556 0.882353
27 GAV 0.550847 0.850575
28 GKD 0.547619 0.872093
29 GP2 0.54386 0.850575
30 GPD 0.543307 0.863636
31 TPG 0.539568 0.791667
32 MD1 0.536232 0.815217
33 JB3 0.534351 0.883721
34 G2P 0.533898 0.850575
35 GPG 0.532787 0.894118
36 YGP 0.532258 0.842697
37 NGD 0.530303 0.916667
38 ALF 5GP 0.529915 0.811111
39 DBG 0.51773 0.928571
40 ALF GDP 0.516393 0.811111
41 GDP ALF 0.516393 0.811111
42 GDP AF3 0.516393 0.811111
43 0O2 0.508065 0.869048
44 U2G 0.507463 0.852273
45 2MD 0.507353 0.815217
46 MGD 0.507246 0.815217
47 G G 0.5 0.904762
48 G3D 0.495868 0.869048
49 ZGP 0.492647 0.835165
50 GDP 7MG 0.492308 0.894118
51 G4P 0.487805 0.869048
52 KB7 0.487395 0.755556
53 FEG 0.485294 0.844444
54 PGD 0.482517 0.842697
55 G1G 0.478873 0.906977
56 CG2 0.478261 0.852273
57 G4M 0.473684 0.846154
58 KBD 0.472441 0.775281
59 GMP 0.46789 0.776471
60 KBJ 0.458015 0.75
61 GH3 0.456 0.858824
62 FE9 0.455172 0.77
63 BGO 0.453237 0.883721
64 DGT 0.451613 0.818182
65 A G 0.450704 0.892857
66 U A G G 0.447552 0.892857
67 GCP G 0.446154 0.835294
68 3GP 0.444444 0.835294
69 GGM 0.443662 0.906977
70 G A A A 0.440559 0.882353
71 PGD O 0.433333 0.8
72 6G0 0.432 0.894118
73 DGI 0.430894 0.818182
74 G U 0.429577 0.840909
75 GPX 0.426357 0.835294
76 IDP 0.42623 0.857143
77 MGP 0.424 0.894118
78 GTA 0.423358 0.917647
79 2GP 0.420168 0.847059
80 G1R G1R 0.417219 0.883721
81 G C 0.413793 0.840909
82 R7I 0.412698 0.835294
83 R5I 0.412698 0.835294
84 AKW 0.412587 0.875
85 01G 0.407407 0.824176
86 GPC 0.405405 0.804348
87 G U34 0.4 0.831461
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1CLU; Ligand: DBG; Similar sites found with APoc: 86
This union binding pocket(no: 1) in the query (biounit: 1clu.bio1) has 62 residues
No: Leader PDB Ligand Sequence Similarity
1 2X77 GDP None
2 2X77 GDP None
3 3N5C GDP None
4 6A8D GDP None
5 4LC1 GDP 4.81928
6 4LC1 GDP 4.81928
7 5KUT GDP 6.0241
8 5KUT GDP 6.0241
9 3WYA GDP 6.45161
10 3WY9 GDP 6.45161
11 3WY9 GDP 6.45161
12 2HCJ GDP 6.62651
13 3U6B GDP 6.62651
14 3U6B GDP 6.62651
15 2BVN GNP 6.62651
16 2BVN GNP 6.62651
17 1D8T GDP 6.62651
18 5JBQ GDP 6.62651
19 3U6K GDP 6.62651
20 4LPS GDP 6.62651
21 5W75 GDP 7.22892
22 5W7Q GDP 7.22892
23 5W75 GDP 7.22892
24 5W76 GDP 7.22892
25 5W75 GDP 7.22892
26 6G14 G4P 7.22892
27 3CNL GNP 7.83133
28 4P3Y GDP 8.43373
29 4J0Q GDP 9.63855
30 4J0Q GDP 9.63855
31 4J0Q GDP 9.63855
32 4J0Q GDP 9.63855
33 3MD0 GDP 10.241
34 1SKQ GDP 10.241
35 1SKQ GDP 10.241
36 2WIC GNP 11.4458
37 1KK1 GNP 12.0482
38 4NON GDP 12.6506
39 3PQC GDP 14.4578
40 2AWN ADP 16.2651
41 5CK5 GDP 18.6747
42 5CK5 GDP 18.6747
43 5CK5 GDP 18.6747
44 5CK5 GDP 18.6747
45 2FH5 GTP 23.494
46 5H7K GDP 27.7108
47 1YRB GDP 29.5181
48 1YRB GDP 29.5181
49 5YT0 GDP 31.9277
50 5FG3 GDP 31.9277
51 1ZD9 GDP 32.5301
52 1RE0 GDP 32.9268
53 4DCT GDP 33.1325
54 3AQ4 GDP 33.1325
55 2QN6 GDP 33.3333
56 1YZG GDP 33.7349
57 1ZJ6 G3D 34.3373
58 1ZJ6 G3D 34.3373
59 5M04 GDP 39.759
60 1FZQ GDP 40.3614
61 2WJG GDP 40.3614
62 3A1S GDP 44.5783
63 3A1S GDP 44.5783
64 3GJ4 GDP 48.1928
65 3GJ5 GDP 48.1928
66 3GJ7 GDP 48.1928
67 3GJ5 GDP 48.1928
68 3GJ4 GDP 48.1928
69 3GJX GTP 48.1928
70 3REF GDP 48.1928
71 5BXQ GDP 48.7952
72 5BXQ GDP 48.7952
73 3GJ0 GDP 48.7952
74 3GJ3 GDP 48.7952
75 5BXQ GDP 48.7952
76 3CH5 GDP 48.7952
77 1Z0J GTP 48.7952
78 5DI9 GNP 48.7952
79 5DHF GNP 48.7952
80 5UWR GNP 48.7952
81 5UWW GNP 48.7952
82 5UWJ GNP 48.7952
83 1IBR GNP 48.7952
84 5UWI GNP 48.7952
85 5UWH GNP 48.7952
86 5OEC GDP 49.3976
APoc FAQ
Feedback