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Receptor
PDB id Resolution Class Description Source Keywords
1FNN 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM PYROBACULUM AEROPHILUM CDC6 CDC18 ORC1 AAA PROTEIN DNA REPLICATION INITATION FACTOR CELL CYCLE CONTROL FACTOR
Ref.: STRUCTURE AND FUNCTION OF CDC6/CDC18: IMPLICATIONS FOR ORIGIN RECOGNITION AND CHECKPOINT CONTROL. MOL.CELL V. 6 637 2000
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:398;
B:399;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:390;
B:391;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1FNN 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM PYROBACULUM AEROPHILUM CDC6 CDC18 ORC1 AAA PROTEIN DNA REPLICATION INITATION FACTOR CELL CYCLE CONTROL FACTOR
Ref.: STRUCTURE AND FUNCTION OF CDC6/CDC18: IMPLICATIONS FOR ORIGIN RECOGNITION AND CHECKPOINT CONTROL. MOL.CELL V. 6 637 2000
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 1FNN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1FNN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 1FNN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1FNN; Ligand: ADP; Similar sites found with APoc: 679
This union binding pocket(no: 1) in the query (biounit: 1fnn.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1UO4 PIH None
2 3KPE TM3 None
3 6CS9 PIO None
4 1U0J ADP 0.749064
5 4IOK ADP 1.28535
6 4IOK XPO 1.28535
7 1F9V ADP 1.44092
8 2B56 U5P 1.54242
9 3CV2 OXL 1.54242
10 4Q1A UDP 1.78571
11 4Q1A 2XZ 1.78571
12 5W75 GDP 1.79949
13 1Z6T ADP 1.79949
14 1X6V ADP 1.79949
15 5I0H ADP BEF 1.79949
16 4RD0 GDP 1.79949
17 2C77 GNP 1.79949
18 2C78 GNP 1.79949
19 4IHQ ADP 1.79949
20 1SVM ATP 1.85676
21 4TTQ ATP 1.86047
22 1XP8 AGS 1.91257
23 4KBF AMP 1.91781
24 4E03 ADP 1.94175
25 5XKT GNP 2
26 4PPF FLC 2
27 4ZG4 VO4 ADP 2.05656
28 6A20 ADP 2.05656
29 1SKQ GDP 2.05656
30 1IN4 ADP 2.09581
31 5ZBR ANP 2.13333
32 2Y65 ADP 2.19178
33 2O66 FLC 2.22222
34 2VWT PYR 2.24719
35 2ZR9 DTP 2.29226
36 6B4K ANP 2.31362
37 4PJ3 ANP 2.31362
38 2BIF ANP 2.31362
39 2BIF SIN 2.31362
40 1TQ4 GDP 2.31362
41 1K6M AGS 2.31362
42 6FAA ADP 2.31362
43 5MZN ADP 2.31362
44 1YTM ATP 2.31362
45 4FRZ ADP 2.33161
46 4WZ6 ATP 2.41379
47 1D5C GDP 2.46914
48 3ZQ6 ADP ALF 2.46914
49 2ZPA ADP 2.57069
50 4XGU ADP 2.57069
51 5AK0 8V1 2.57069
52 5HR5 ADP 2.57069
53 5KSZ GCP 2.57069
54 1MKY GDP 2.57069
55 1DAR GDP 2.57069
56 1D2E GDP 2.57069
57 1KK1 GNP 2.57069
58 5IRR GSP 2.5974
59 3H86 AP5 2.60417
60 1Z06 GNP 2.6455
61 1M3U KPL 2.65152
62 2OZE AGS 2.68456
63 4H1V GNP 2.71003
64 4PX9 ADP 2.73973
65 1VHT BA3 2.75229
66 5M04 GDP 2.77778
67 3T34 GDP 2.77778
68 1NJF ADP 2.8
69 1NJF AGS 2.8
70 5J1J ANP 2.80702
71 1VKJ A3P 2.80702
72 3MD0 GDP 2.8169
73 3G5N PB2 2.82776
74 1YQT ADP 2.82776
75 4DCT GDP 2.82776
76 5ZXD ATP 2.82776
77 3IO3 ADP 2.82776
78 5JCP GDP ALF 2.82776
79 5YV5 ADP 2.82776
80 4WOP CTP 2.82776
81 2DPY ADP 2.82776
82 1OFD FMN 2.82776
83 1OFD AKG 2.82776
84 4D42 NAP 2.83688
85 4D42 W0I 2.83688
86 1M7G AV2 2.8436
87 1M7G ADX 2.8436
88 1M7G ADP 2.8436
89 2O0J ADP 2.85714
90 5K5Z ANP 2.86624
91 3LN9 FLC 2.8777
92 3TBK ANP 2.88288
93 2F3R G5P 2.89855
94 3DC4 ADP 2.90698
95 2FFQ GSP 2.92398
96 1YZQ GNP 2.94118
97 4Z7X 3CX 2.94118
98 2V2V V12 2.95203
99 1Z2A GDP 2.97619
100 4NE2 SH2 2.99401
101 4NE2 ADP 2.99401
102 4J0Q GDP 3.00231
103 2JBM SRT 3.01003
104 2QG6 NMN 3.01508
105 2F7A BEZ 3.01724
106 3TK1 GDP 3.0303
107 1YRB GDP 3.05344
108 2PZE ATP 3.05677
109 4NON GDP 3.07692
110 2GK6 ADP 3.08483
111 5N69 ADP 3.08483
112 4NCN GTP 3.08483
113 2D7D ADP 3.08483
114 2QEN ADP 3.14286
115 2IYL GDP 3.16901
116 5JCA FAD 3.16901
117 4TMZ GSP 3.18841
118 6B8B ADP 3.21285
119 2BME GNP 3.22581
120 1SQ5 ADP 3.24675
121 1O68 KIV 3.27273
122 4U00 ADP 3.27869
123 5OWC AYZ 3.27869
124 4ZNL BEF ADP 3.28467
125 1ZRH A3P 3.28467
126 1GXU 2HP 3.2967
127 1WDT GTP 3.3419
128 5Y6N ADP 3.3419
129 3EZ2 ADP 3.3419
130 2XT3 ADP 3.3419
131 4A4Z ANP 3.3419
132 2A2C NG1 3.3419
133 2A2C ADP 3.3419
134 2FSH ANP 3.3419
135 4JLV ADP 3.34572
136 1NY5 ADP 3.35917
137 2OFW ADX 3.36538
138 1XMV ADP 3.37079
139 2CBZ ATP 3.37553
140 3GUZ PAF 3.40909
141 2VVG ADP 3.42857
142 1B0U ATP 3.43511
143 1FP6 ADP 3.46021
144 3A4M ADP 3.46154
145 1OE0 TTP 3.47826
146 1Z0K GTP 3.48837
147 4YDS ATP 3.50877
148 1R2Q GNP 3.52941
149 4LC1 GDP 3.56083
150 5M7P ADP 3.59897
151 6DEF GCP 3.59897
152 4IDN GNP 3.59897
153 2FAH GDP 3.59897
154 3QDK QDK 3.59897
155 4WZA ADP 3.62319
156 4WZA ACP 3.62319
157 1E2K TMC 3.62538
158 3VX3 ADP 3.62903
159 4QEK GLC 3.65448
160 1XX6 ADP 3.66492
161 1M2O GNP 3.68421
162 4R98 GNH 3.69004
163 1BG2 ADP 3.69231
164 5BQ5 ADP BEF 3.7037
165 2WIC GNP 3.74532
166 5UPK GNP 3.78378
167 4DDY DN6 3.80228
168 2PL3 ADP 3.81356
169 2VOH CIT 3.82166
170 1D8T GDP 3.85604
171 5JBQ GDP 3.85604
172 4G5G GDP 3.85604
173 4WEI GLC GAL 3.85604
174 4P3Y GDP 3.85604
175 3U6B GDP 3.85604
176 3U6K GDP 3.85604
177 2BVN GNP 3.85604
178 4M52 FAD 3.85604
179 5BYK OAQ 3.861
180 5BYK A3P 3.861
181 3T5G GDP 3.8674
182 4YC7 GNP 3.8674
183 2BCG GDP 3.8835
184 5W76 GDP 3.8961
185 2PEZ GGZ 3.91061
186 2PEZ DAT 3.91061
187 3NHB ADP 3.92157
188 3CX8 GSP 3.94089
189 1RYH GNP 3.94089
190 1GOJ ADP 3.94366
191 5UIV ADP 3.96476
192 5W7Q GDP 4.02145
193 2OBM ADP 4.03458
194 3CPJ GDP 4.03587
195 3FYH ADP 4.03727
196 3DKP ADP 4.08163
197 1R6B ADP 4.11311
198 4HSE ADP 4.11311
199 5U32 GDP 4.11311
200 2G77 GDP 4.11311
201 5H68 AGS 4.11765
202 1QF9 ALF 4.12371
203 1QF9 ADP 4.12371
204 1QF9 C5P 4.12371
205 3REF GDP 4.12371
206 1ZCB GDP 4.14365
207 4DKX GDP 4.16667
208 1NN5 2DT 4.18605
209 1NN5 ANP 4.18605
210 2QTV GNP 4.19162
211 5KUT GDP 4.2328
212 4D81 ADP 4.24028
213 1G6O ADP 4.24242
214 2WJG GDP 4.25532
215 2XTN GTP 4.2735
216 3SBD GNP 4.27807
217 2YOH WMJ 4.28571
218 1Y63 ADP 4.34783
219 4OI4 ATP 4.34783
220 5TIV A3P 4.34783
221 2GWH A3P 4.36242
222 4AG5 ADP 4.37018
223 4IEE AGS 4.37018
224 3EWA ANP 4.37018
225 1LVK MNT BEF 4.37018
226 1UJ2 C5P 4.37018
227 1UJ2 ADP 4.37018
228 1CR1 TTP 4.37018
229 2IXE ATP 4.42804
230 3FVQ ATP 4.45682
231 5XQL C2E 4.46735
232 2GCO GNP 4.47761
233 2GCN GDP 4.47761
234 2EFE GNH 4.49438
235 4U5X GNP 4.49438
236 3UIE ANP 4.5
237 2XTZ GSP 4.51977
238 3VMF GTP 4.55764
239 5O74 GDP 4.56853
240 3NKV GNP 4.57143
241 3CNL GNP 4.58015
242 3COB ADP 4.60705
243 1ZIN AP5 4.60829
244 1JJ7 ADP 4.61538
245 1SVI GDP 4.61538
246 3DZD ADP 4.61957
247 3KTA AP5 4.62428
248 1OS1 PYR 4.62725
249 1OS1 ATP 4.62725
250 2XAU ADP 4.62725
251 3WYA GDP 4.62725
252 3WY9 GDP 4.62725
253 4YS0 ADP 4.62725
254 3B2Q AES 4.62725
255 1QHG ATP 4.62725
256 1T9D P22 4.62725
257 2GMV UN8 4.62725
258 1XEX ATP 4.65116
259 4V03 ADP 4.66926
260 2ORV 4TA 4.70085
261 5LEF GTP 4.71204
262 4KFU ACP 4.71698
263 3Q85 GNP 4.73373
264 4TL6 ANP 4.74308
265 2ZPT A3P 4.74576
266 3QVV A3P 4.74576
267 3QVV 3QV 4.74576
268 4KVG GTP 4.7619
269 1G3M PCQ 4.7619
270 1G3M A3P 4.7619
271 3B7G ANP 4.78261
272 3X1Z GNP 4.79042
273 4GOX A3P 4.79233
274 3BFV ADP 4.79705
275 1ZJ6 G3D 4.81283
276 1CLU DBG 4.81928
277 3LXR GDP 4.86486
278 6BCB GSP 4.86486
279 4D0N GDP 4.86486
280 5G3Y ADP 4.86726
281 4R2I ANP 4.88432
282 4L80 OXL 4.88506
283 2Q2Y ADP 4.90463
284 2Q2Y MKR 4.90463
285 1NST A3P 4.92308
286 2GDJ ANP 4.92424
287 5G41 AP5 4.93274
288 1GUA GNP 4.93827
289 1AKY AP5 5
290 2F9L GDP 5.02513
291 2Y8E GNP 5.02793
292 1YZG GDP 5.02793
293 6AU6 GDP 5.03979
294 3E5H GNP 5.05618
295 1S3G AP5 5.06912
296 4NU0 AP5 5.06912
297 4MKG AP5 5.06912
298 4MKF AP5 5.06912
299 3P4X ADP 5.08475
300 5WC2 ADP 5.14139
301 3FKQ ATP 5.14139
302 3EC1 GDP 5.14139
303 3H4S ADP 5.18518
304 2CJW GDP 5.20833
305 3BER AMP 5.22088
306 1OIX GDP 5.2356
307 1OIV GDP 5.2356
308 3IUY AMP 5.26316
309 4JLS 3ZE 5.26316
310 4P4T GDP 5.27778
311 4M9Q GNP 5.28634
312 1Z08 GNP 5.29412
313 5GT9 NAP 5.32319
314 3KC1 2T6 5.34125
315 2JAQ DCP 5.36585
316 1KSH GDP 5.37634
317 1OXV ANP 5.38244
318 5LB3 ADP 5.39846
319 1JQ3 AAT 5.40541
320 1X8J A3P 5.41311
321 1UKZ ADP 5.41872
322 3GJ7 GDP 5.42986
323 3GJ0 GDP 5.42986
324 3GJ3 GDP 5.42986
325 3GJ4 GDP 5.42986
326 1G6H ADP 5.44747
327 5EP2 AZU 5.46875
328 2EW1 GNP 5.47264
329 4B47 GDP 5.50964
330 3FB4 AP5 5.55556
331 1IBR GNP 5.55556
332 5ZB0 TYD 5.55556
333 5ZB0 ADP 5.55556
334 4X8O AP5 5.60748
335 5Z69 AGS 5.64516
336 4LX0 BEF GDP 5.64972
337 1S8F GDP 5.64972
338 2FNA ADP 5.65553
339 4YJ1 ADP 5.65553
340 1Q20 A3P 5.68562
341 1Q20 PLO 5.68562
342 1T5C ADP 5.73066
343 3TNF GNP 5.74713
344 2B6N ALA PRO THR 5.7554
345 3Q9L ATP 5.76923
346 1OW3 GDP 5.78512
347 2B8W ALF 5GP 5.79268
348 1DAK DPU 5.80357
349 1DAK ADP 5.80357
350 4GOJ GNP 5.82011
351 1JJV ATP 5.82524
352 1JI0 ATP 5.83333
353 1D2N ANP 5.88235
354 3GJ5 GDP 5.88235
355 3W5J GDP 5.88235
356 1IHU AF3 5.9126
357 1IHU ADP 5.9126
358 1P72 ADP 5.9126
359 6G14 G4P 5.9126
360 5VHC BEF ADP 5.9126
361 5XDR ADP 5.9126
362 4BFW ZVW 5.9126
363 2ZJ5 ADP 5.9126
364 5IRC GDP 5.91398
365 3ZS9 ADP ALF 5.9322
366 2WOJ ADP ALF 5.9322
367 5DI3 GNP 5.94595
368 1KMQ GNP 5.97826
369 5GVR LMR 5.98291
370 2WKQ GTP 6.0241
371 3Q72 GNP 6.0241
372 2W83 GTP 6.06061
373 3AB3 GDP 6.09756
374 3IIJ ADP 6.11111
375 2J0V GDP 6.13208
376 2RCN GDP 6.14525
377 5EXT ADP 6.15385
378 5TSH ANP 6.16967
379 5LTJ ADP 6.16967
380 5H7J GCP 6.16967
381 4ZKD GDP 6.16967
382 5LTJ BEF 6.16967
383 5TSH ADP 6.16967
384 4OHY ANP 6.16967
385 5H7K GDP 6.16967
386 3B5J 12D 6.17284
387 3N5C GDP 6.17284
388 5MVR ADP 6.17284
389 3BOS CDP 6.19835
390 2BEK ATP 6.22568
391 1KO8 6PG 6.28571
392 2AWN ADP 6.29921
393 2HT6 GDP 6.32184
394 1TU3 GNP 6.32911
395 1G7C 5GP 6.38298
396 4XSH GSP 6.39269
397 1AQU A3P 6.39731
398 5SZH GNP 6.40394
399 3WYF GTP 6.42674
400 2IS6 ADP 6.42674
401 3RC3 ANP 6.42674
402 4RZ3 ADP 6.44068
403 2CDN ADP 6.46766
404 3RAB GNP 6.50888
405 4REI 3MV 6.62252
406 3SFV GDP 6.62983
407 3TKL GTP 6.63265
408 1W4R TTP 6.66667
409 1W0J ADP BEF 6.6838
410 1W0J ADP 6.6838
411 2FJU GSP 6.6838
412 1NBU PH2 6.72269
413 3AB4 THR 6.74157
414 4FCW ADP 6.75241
415 5KDO GDP 6.75676
416 1SVK ALF GDP 6.79887
417 1WA5 GTP 6.81818
418 1SQL GUN 6.84932
419 2A5F GTP 6.85714
420 3DEF GDP 6.87023
421 2NCD ADP 6.94087
422 3WXM GTP 6.94087
423 1V59 FAD 6.94087
424 1G8S MET 6.95652
425 1WF3 GNP 6.97674
426 2GJ8 ALF GDP 6.97674
427 1T8U UAP SGN IDS SGN 6.98529
428 1T8U A3P 6.98529
429 5WDR GNP 7.01754
430 4QM7 GTP 7.01754
431 3RWO GDP 7.02703
432 4XOI GTP 7.03704
433 3LRE ADP 7.04225
434 1EK0 GNP 7.05882
435 3T12 GDP ALF 7.07071
436 3T1O GDP 7.07071
437 3QKT ANP 7.07965
438 4JD3 PLM 7.08215
439 4JD3 COA 7.08215
440 3KJI ADP 7.08661
441 3PQC GDP 7.17949
442 4KVA GTP 7.19794
443 2VB6 ADP BEF 7.19794
444 4PFO ADP 7.19794
445 1OYY AGS 7.19794
446 2QZ4 ADP 7.25191
447 4PTN PYR 7.28863
448 2ZFI ADP 7.37705
449 2OM2 GDP 7.38462
450 4LYA ATP 7.45501
451 4LHW GNP 7.47126
452 1Z0A GDP 7.47126
453 1LVG ADP 7.57576
454 1HTW ADP 7.59494
455 5EE5 GTP 7.60234
456 1UPT GTP 7.60234
457 2J5V PCA 7.62943
458 5UWS GNP 7.69231
459 5UWQ GNP 7.69231
460 5UWW GNP 7.69231
461 5UWP GNP 7.69231
462 5UWI GNP 7.69231
463 5DIF GNP 7.69231
464 5UWT GNP 7.69231
465 5UWJ GNP 7.69231
466 5UWR GNP 7.69231
467 6CIT GNP 7.69231
468 5UWU GNP 7.69231
469 5DHF GNP 7.69231
470 5UWH GNP 7.69231
471 4KAX GTP 7.69231
472 1CXZ GSP 7.69231
473 5DI9 GNP 7.69231
474 5BN3 ADP 7.71208
475 1XKV ATP 7.71208
476 5GOE GDP 7.71208
477 6BCA GSP 7.71208
478 1E1M NAP 7.71208
479 1E1M FAD 7.71208
480 1ZUI SKM 7.7381
481 3BFX A3P 7.77027
482 5WRI A3P 7.8125
483 2WJH GDP 7.83133
484 2WJH FLC 7.83133
485 4LPS GDP 7.85124
486 4HAT GNP 7.85714
487 3QBT GNP 7.85714
488 3KP6 SAL 7.94702
489 5XC5 GTP 7.95455
490 2GKS ADP 7.96915
491 5FG3 GDP 7.96915
492 1F6B GDP 8.08081
493 3MGB PAP 8.15047
494 1VG8 GNP 8.21256
495 1VG0 GDP 8.21256
496 1G41 ADP 8.22622
497 5JCZ GDP 8.22622
498 4R43 GDP 8.22622
499 1KY3 GDP 8.24176
500 5WRJ A3P 8.25082
501 5DKK FMN 8.27586
502 1GOT GDP 8.28571
503 4QOS ADP 8.30189
504 5E5U MLI 8.33333
505 6AIC AMP 8.41121
506 3RLF ANP 8.42105
507 1G7S GDP 8.48329
508 1H65 GDP 8.51852
509 3FWY ADP 8.59873
510 4GBM A3P 8.66873
511 3HU3 AGS 8.74036
512 4XTR ATP 8.75576
513 4XVU ATP 8.75576
514 4XTR ADP 8.75576
515 2W2X GSP 8.87097
516 5X40 ACP 8.90411
517 2W58 ADP 8.91089
518 5UQW GDP 8.99471
519 5OCG GNP 8.99471
520 4HI0 GDP 9.04523
521 4BAS GNP 9.04523
522 4BQS ADP 9.09091
523 4BQS K2Q 9.09091
524 1VG1 GDP 9.18919
525 1VG9 GDP 9.18919
526 5TAR GDP 9.18919
527 5TB5 GDP 9.18919
528 1FQK GDP 9.23077
529 1V8K ANP 9.2545
530 1TAD GDP 9.25926
531 1TAD ALF 9.25926
532 5VGR GDP 9.28074
533 2HF9 GSP 9.29204
534 4HDO GNP 9.31677
535 4HDQ GNP 9.31677
536 2HV8 GTP 9.375
537 4CVN ADP 9.48905
538 2QN6 GDP 9.67742
539 3TMK T5A 9.72222
540 2ZX2 RAM 9.74359
541 6FA4 GNP 9.82659
542 5J1S ATP 9.85915
543 4P83 U5P 9.89011
544 2WHX ADP 10.0257
545 2JLR ANP 10.0257
546 5O2T GSP 10.0592
547 3A1S GDP 10.0775
548 1NRJ GTP 10.1266
549 6BVM GNP 10.1796
550 6D5L GNP 10.1796
551 6D59 GNP 10.1796
552 6BVJ GNP 10.1796
553 6BVL GNP 10.1796
554 6BVI GNP 10.1796
555 6BVK GNP 10.1796
556 6D56 GNP 10.1796
557 6D55 GNP 10.1796
558 6D5J GNP 10.1796
559 6D5G GNP 10.1796
560 6D5H GNP 10.1796
561 6D5E GNP 10.1796
562 6D5M GNP 10.1796
563 6D5V GNP 10.1796
564 1CS4 GSP 10.2222
565 5BXQ GDP 10.2362
566 3KUD GDP 10.241
567 1WQ1 GDP 10.241
568 3DDC GNP 10.241
569 1NVV GNP 10.241
570 3ZFD ANP 10.2564
571 5IRN ADP 10.2828
572 1OFH ADP 10.3226
573 2A5J GDP 10.4712
574 2KIN ADP 10.5042
575 1W7J ADP BEF 10.596
576 3K8D KDO 10.6061
577 5FHD ADP ALF 10.7969
578 5FTB ANP 10.7969
579 6C90 ADP 10.7969
580 3GJX GTP 10.7969
581 4PC3 GDP 10.9929
582 2C9O ADP 11.054
583 4UMJ BFQ 11.1486
584 2A9K GDP 11.2108
585 5E95 GDP 11.3402
586 2ZE7 AMP 11.4625
587 2ZE7 DST 11.4625
588 5OEC GDP 11.4754
589 1ZD9 GDP 11.7021
590 3ZO7 K6H 11.7021
591 3MJH GTP 11.7647
592 2F5Z FAD 11.8252
593 1L2T ATP 11.9149
594 3GJ8 GDP 11.9565
595 5U8U FAD 12.0823
596 3DOE GTP 12.1212
597 1Z0F GDP 12.2905
598 1YZN GNP 12.4324
599 1R0X ATP 12.5874
600 1RRC ADP 12.6246
601 1TX4 ALF GDP 12.6263
602 2CHG ANP 12.8319
603 2Z5F A3P 12.8535
604 4YMU ATP 12.9167
605 4YLG GDP 13.2948
606 4ZI2 GNP 13.5338
607 4HDK 13X 13.6247
608 5IFS ADP 13.9241
609 5KSP GDP 14.2105
610 5HPY GDP 14.2241
611 3ZIA ADP 14.2857
612 3ZIA ATP 14.2857
613 2D7C GTP 14.2857
614 1QHH ATP 14.3713
615 4L9Z OXL 14.4543
616 2X77 GDP 14.8148
617 2UZI GTP 14.9123
618 5UWO GNP 15
619 4DID GDP 15.0259
620 2RGX AP5 15.0485
621 4V1F BQ1 15.1163
622 1NF3 GNP 15.3846
623 2ZTS ADP 15.5378
624 1GRN GDP 15.7068
625 1A4R GNH 15.7068
626 1A4R GDP 15.7068
627 4ITR GDP 15.7068
628 2NGR GDP 15.7068
629 2WMO GTP 15.7895
630 5Z2M GTP 15.942
631 4V0K GDP 15.9763
632 1UAD GNP 16.1616
633 1F2U ATP 16.2162
634 2HCJ GDP 16.2162
635 2ODE ALF GDP 16.3121
636 2D2F ADP 16.8
637 6CRK GDP 16.9014
638 1GP2 GDP 16.9014
639 1B7T ADP 17.3077
640 1Z0J GTP 17.6471
641 1YVD GNP 17.7515
642 2QQ0 ANP 17.9348
643 2QQ0 THM 17.9348
644 2QQ0 TMP 17.9348
645 2QQ0 ADP 17.9348
646 2ZEJ GDP 18.4783
647 3BC1 GNP 18.6441
648 5H67 ATP 18.75
649 2C5L GTP 18.8034
650 3AQ4 GDP 19.0217
651 1R4A GNP 19.6078
652 3PCR GTP 20.9877
653 3WYG GTP 21.0526
654 1FQJ GDP 21.4286
655 1J2J GTP 21.6867
656 1O3Y GTP 21.6867
657 2J59 GTP 21.6867
658 1S9D GDP 21.9512
659 1RE0 GDP 21.9512
660 2V7Q ADP 22
661 2V7Q ATP 22
662 2CK3 ANP 22
663 2CK3 ADP 22
664 3I6B KDO 22.2222
665 1Z83 AP5 22.449
666 3DUV KDO 22.5191
667 4C4P GNP 23.3645
668 5HCN GCP 24.1379
669 4LJ9 ACP 24.1888
670 5WLB GNP 26.4706
671 1KK8 BEF ADP 29.4964
672 2CE7 ADP 30.3342
673 6BC0 GSP 30.6667
674 1LFD GNP 35.6322
675 3QF7 ANP 36
676 5YT0 GDP 42.8571
677 4D0G GTP 43.4783
678 1W5T ANP 47.5578
679 1W5T ADP 47.5578
Pocket No.: 2; Query (leader) PDB : 1FNN; Ligand: ADP; Similar sites found with APoc: 13
This union binding pocket(no: 2) in the query (biounit: 1fnn.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 5OKT 9XK 1.91083
2 6G5J EM8 2.42424
3 3R7F CP 2.63158
4 5NM7 GLY 3.38346
5 3KDU NKS 4.33213
6 1NHX FTB 4.62725
7 1NHX PEP 4.62725
8 5OSW DIU 4.62725
9 4TO8 FLC 5.13699
10 2V2G BEZ 7.72532
11 3LU1 NAD 8.24176
12 5J5Z FAD 11.8252
13 3RMK BML 12.0482
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