Receptor
PDB id Resolution Class Description Source Keywords
1EWJ 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WITH BLEOMYCIN KLEBSIELLA PNEUMONIAE BLEOMYCIN-BINDING PROTEIN BLEOMYCIN ANTIBIOTICS RESISTANCE HOMODIMER ANTIBIOTIC INHIBITOR
Ref.: CRYSTAL STRUCTURES OF THE TRANSPOSON TN5-CARRIED BLEOMYCIN RESISTANCE DETERMINANT UNCOMPLEXED AND COMPLEXED WITH BLEOMYCIN. J.BIOL.CHEM. V. 276 9992 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BLM A:1001;
B:1002;
C:1004;
D:1003;
E:2001;
F:2002;
G:2004;
H:2003;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
1416.56 C55 H85 N17 O21 S3 Cc1c(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1EWJ 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WITH BLEOMYCIN KLEBSIELLA PNEUMONIAE BLEOMYCIN-BINDING PROTEIN BLEOMYCIN ANTIBIOTICS RESISTANCE HOMODIMER ANTIBIOTIC INHIBITOR
Ref.: CRYSTAL STRUCTURES OF THE TRANSPOSON TN5-CARRIED BLEOMYCIN RESISTANCE DETERMINANT UNCOMPLEXED AND COMPLEXED WITH BLEOMYCIN. J.BIOL.CHEM. V. 276 9992 2001
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BLM; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 BLM 1 1
2 BY6 CU 0.755102 0.873563
3 CU BLM 0.673077 0.943182
4 52G 0.553648 0.855556
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1ewj.bio4) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: 25
This union binding pocket(no: 2) in the query (biounit: 1ewj.bio4) has 32 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1A78 TDG 0.03948 0.40749 2.38095
2 1W6P NDG GAL 0.01846 0.4147 3.1746
3 5BVE 4VG 0.01127 0.40201 3.1746
4 5EW9 5VC 0.01451 0.41501 3.96825
5 4FFG 0U8 0.02523 0.42038 4.7619
6 4FFG LBS 0.01786 0.41235 4.7619
7 1VJ7 GDP 0.03545 0.40923 4.7619
8 5AIG VPR 0.03706 0.40294 4.8
9 3SAO DBH 0.005039 0.44843 5.55556
10 3SAO NKN 0.0127 0.42311 5.55556
11 2YMZ LAT 0.01037 0.40154 5.55556
12 1JL0 PUT 0.04665 0.40079 5.55556
13 5DG2 GAL GLC 0.01125 0.40111 6.34921
14 1J1R ADE 0.04403 0.40438 7.93651
15 1OGZ EQU 0.0229 0.40635 8.8
16 4EE7 PIS 0.001775 0.46437 9.52381
17 4DSU BZI 0.02754 0.41998 9.52381
18 1JJ7 ADP 0.04752 0.40349 11.1111
19 1NJJ GET 0.01847 0.41481 11.9048
20 3WG3 A2G GAL NAG FUC 0.03838 0.40764 11.9048
21 5CJ3 52G 0.00004373 0.46575 12.6984
22 2QL9 CIT 0.007035 0.44525 12.6984
23 4QCK ASD 0.01008 0.42024 16.6667
24 1SDW IYT 0.02713 0.40267 19.0476
25 1JIF CU BLM 0.0000265 0.49311 39.3443
Pocket No.: 3; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: 9
This union binding pocket(no: 3) in the query (biounit: 1ewj.bio2) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1ULE GLA GAL NAG 0.01736 0.42243 None
2 2CB8 MYA 0.04549 0.40018 2.29885
3 1ZP9 ATP 0.0232 0.40022 2.38095
4 3TY3 GGG 0.0303 0.40945 4.7619
5 1OGX EQU 0.01997 0.40338 4.7619
6 3GM5 CIT 0.001092 0.48855 6.34921
7 4MPO AMP 0.02468 0.41098 6.34921
8 4OPC FDA 0.01078 0.4245 7.14286
9 2Z77 NCA 0.02225 0.4164 18.254
Pocket No.: 4; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1ewj.bio2) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: 14
This union binding pocket(no: 5) in the query (biounit: 1ewj.bio3) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SN0 T44 0.007077 0.42915 None
2 3ZW0 FUC 0.02304 0.41727 None
3 4CSD MFU 0.03858 0.4045 None
4 1OFL NGK GCD 0.0276 0.40713 2.38095
5 1YXM ADE 0.03465 0.40655 4.7619
6 3RGA LSB 0.01623 0.4043 6.34921
7 1KJ1 MAN 0.01087 0.42262 6.42202
8 4D4U FUC GAL 0.0236 0.41877 11.1111
9 4XBT 3ZQ 0.01456 0.4137 14.2857
10 4XBT FLC 0.01958 0.40379 14.2857
11 4FXQ G9L 0.04185 0.40211 17.4603
12 4FK7 P34 0.0279 0.40126 17.4603
13 4YGM URA 0.03738 0.41468 23.0159
14 3ZGJ RMN 0.01318 0.42401 26.9841
Pocket No.: 6; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1ewj.bio3) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: 3
This union binding pocket(no: 7) in the query (biounit: 1ewj.bio1) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4BCS BTN 0.01585 0.40603 None
2 2YKL NLD 0.0163 0.41252 5.55556
3 4UXU MLK 0.03214 0.40005 6.34921
Pocket No.: 8; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1ewj.bio1) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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