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Receptor
PDB id Resolution Class Description Source Keywords
1EWJ 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WIT BLEOMYCIN KLEBSIELLA PNEUMONIAE BLEOMYCIN-BINDING PROTEIN BLEOMYCIN ANTIBIOTICS RESISTANCEHOMODIMER ANTIBIOTIC INHIBITOR
Ref.: CRYSTAL STRUCTURES OF THE TRANSPOSON TN5-CARRIED BL RESISTANCE DETERMINANT UNCOMPLEXED AND COMPLEXED WI BLEOMYCIN. J.BIOL.CHEM. V. 276 9992 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BLM A:1001;
B:1002;
C:1004;
D:1003;
E:2001;
F:2002;
G:2004;
H:2003;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
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1416.56 C55 H85 N17 O21 S3 Cc1c(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1EWJ 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WIT BLEOMYCIN KLEBSIELLA PNEUMONIAE BLEOMYCIN-BINDING PROTEIN BLEOMYCIN ANTIBIOTICS RESISTANCEHOMODIMER ANTIBIOTIC INHIBITOR
Ref.: CRYSTAL STRUCTURES OF THE TRANSPOSON TN5-CARRIED BL RESISTANCE DETERMINANT UNCOMPLEXED AND COMPLEXED WI BLEOMYCIN. J.BIOL.CHEM. V. 276 9992 2001
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 1EWJ - BLM C55 H85 N17 O21 S3 Cc1c(nc(nc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BLM; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 BLM 1 1
2 52G 0.553648 0.855556
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 77
This union binding pocket(no: 1) in the query (biounit: 1ewj.bio4) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 6GNO XDI None
2 2BS5 BGC GAL FUC None
3 1ULE GLA GAL NAG None
4 4B1M FRU FRU None
5 4BCS BTN None
6 4CNO 9PY None
7 4OIT MAN None
8 1RTF BEN 1.5873
9 43CA NPO 1.76991
10 2AGC DAO 2.38095
11 1W6P NDG GAL 3.1746
12 1CEB AMH 3.40909
13 5EW9 5VC 3.96825
14 5JOG 6LT 3.96825
15 6BU0 IHP 4.7619
16 3WWX DIA 4.7619
17 1VJ7 GDP 4.7619
18 4FFG 0U8 4.7619
19 2ZSC BTN 4.7619
20 3ZXE PGZ 4.7619
21 4WOE ADP 4.7619
22 4FFG LBS 4.7619
23 5TZO 7V7 4.7619
24 5Z54 0HZ 4.7619
25 1UW1 ADP 5
26 3SAO DBH 5.55556
27 3SAO NKN 5.55556
28 2YMZ LAT 5.55556
29 2YKL NLD 5.55556
30 4JH6 FCN 5.55556
31 4JNJ BTN 6.08696
32 3GM5 CIT 6.34921
33 6C0B MLI 6.34921
34 5DG2 GAL GLC 6.34921
35 4UXU MLK 6.34921
36 3RGA LSB 6.34921
37 1KJ1 MAN 6.42202
38 5B09 4MX 6.73077
39 4OPC FDA 7.14286
40 4OPC PGT 7.14286
41 1ELI PYC 7.93651
42 2AWN ADP 7.93651
43 1U6R ADP 7.93651
44 5KJW 53C 7.93651
45 4M1U A2G MBG 8.57143
46 6EK3 OUL 8.73016
47 3M3E GAL A2G NPO 8.73016
48 4GAH 0ET 8.73016
49 1OGZ EQU 8.8
50 4EE7 PIS 9.52381
51 6FA4 D1W 9.52381
52 4D4U FUC GAL NAG 11.1111
53 4D52 GXL 11.1111
54 4D52 GIV 11.1111
55 1JJ7 ADP 11.1111
56 1VRP ADP 11.1111
57 4D4U FUC GAL 11.1111
58 5Y4K AKR 11.9048
59 5CJ3 52G 12.6984
60 2QL9 CIT 12.6984
61 6DZN AE3 13.4921
62 3PPQ CHT 13.4921
63 6E1Q CFA 13.4921
64 3WR7 SPD 13.4921
65 1SWG BTN 15.873
66 4QCK ASD 16.6667
67 1RRC ADP 17.4603
68 2Z77 NCA 18.254
69 5F1V 3VN 18.254
70 5L6G XYP 19.0476
71 1SDW IYT 19.0476
72 2P7Q GG6 20.6349
73 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU 21.0526
74 1FDJ 13P 23.0159
75 4YGM URA 23.0159
76 4G7A AZM 25.3968
77 1JIF CU BLM 39.3443
Pocket No.: 2; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 23
This union binding pocket(no: 2) in the query (biounit: 1ewj.bio4) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 4OIT BMA None
2 3HAV ATP None
3 4LIK CIT None
4 3NNT DQA None
5 5H4S RAM 2.38095
6 1A78 TDG 2.38095
7 5VGS 9A7 2.38095
8 5H9P TD2 3.96825
9 5H9Q TD2 4.7619
10 3WV6 GAL BGC 4.7619
11 1OGX EQU 4.7619
12 5AIG VPR 4.8
13 2D6M LBT 5.55556
14 1C9K 5GP 6.34921
15 5O0J 8BR 7.93651
16 1J1R ADE 7.93651
17 5ZI9 FLC 10.3175
18 1NJJ GET 11.9048
19 3WG3 A2G GAL NAG FUC 11.9048
20 3WUD GLC GAL 12.6984
21 1OFZ FUC 18.254
22 2Z77 HE7 18.254
23 4OGQ 7PH 41.1765
Pocket No.: 3; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 14
This union binding pocket(no: 3) in the query (biounit: 1ewj.bio2) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 4YLZ LAT NAG GAL None
2 2CB8 MYA 2.29885
3 5LXB 7A9 2.38095
4 1ZP9 ATP 2.38095
5 1FLJ GSH 3.96825
6 3TY3 GGG 4.7619
7 5GLT BGC GAL NAG GAL 4.7619
8 1Z03 OCH 5.55556
9 2GOO NDG 6.14035
10 4MPO AMP 6.34921
11 5W1E PHB 7.14286
12 5TCI MLI 7.93651
13 3I4X DST 11.1111
14 1NKI PPF 26.6667
Pocket No.: 4; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 9
This union binding pocket(no: 4) in the query (biounit: 1ewj.bio2) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 1NE6 SP1 None
2 1C1L GAL BGC None
3 4CSD MFU None
4 6F7X MFU None
5 2XMY CDK 3.1746
6 5K21 6QF 3.96825
7 5NCF 8T5 6.19469
8 5INJ 6C7 7.14286
9 2PX8 MGT 8.73016
Pocket No.: 5; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 17
This union binding pocket(no: 5) in the query (biounit: 1ewj.bio3) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 3ZW0 FUC None
2 4Y24 TD2 None
3 3ZW2 NAG GAL FUC None
4 3ZW2 GAL FUC None
5 2AG4 LP3 2.38095
6 2AG4 OLA 2.38095
7 1OFL NGK GCD 2.38095
8 1Y2F WAI 2.38095
9 1B4P GPS 2.38095
10 5LX9 OLB 3.96825
11 1YXM ADE 4.7619
12 3WW2 SF9 7.93651
13 4JX1 CAH 15.873
14 4FXQ G9L 17.4603
15 4FK7 P34 17.4603
16 5ZCO CHD 19.2661
17 3ZGJ RMN 26.9841
Pocket No.: 6; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 4
This union binding pocket(no: 6) in the query (biounit: 1ewj.bio3) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 1FIW PBZ 3.96825
2 2P41 G1G 6.34921
3 5A6B OAN 7.14286
4 4CJN QNZ 7.14286
Pocket No.: 7; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 1
This union binding pocket(no: 7) in the query (biounit: 1ewj.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 5LHT TIH 8.73016
Pocket No.: 8; Query (leader) PDB : 1EWJ; Ligand: BLM; Similar sites found with APoc: 6
This union binding pocket(no: 8) in the query (biounit: 1ewj.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZU4 4TG 1.5873
2 1W6M GAL 3.1746
3 6G7N DAL 4.7619
4 4J0M BLD 5.55556
5 1IA7 BGC BGC 6.34921
6 5XIO HFG 9.52381
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