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Receptor
PDB id Resolution Class Description Source Keywords
1DCP 2.3 Å EC: 4.2.1.96 DCOH, A BIFUNCTIONAL PROTEIN-BINDING TRANSCRIPTIONAL COACTIVATOR, COMPLEXED WITH BIOPTERIN RATTUS NORVEGICUS TRANSCRIPTIONAL STIMULATOR DIMERIZATION COFACTOR DEHYDRATASE 4A-CARBINOLAMINE DEHYDRATASE TRANSREGULATOR OF HOMEODOMAIN PROTEINS
Ref.: HIGH-RESOLUTION STRUCTURES OF THE BIFUNCTIONAL ENZYME AND TRANSCRIPTIONAL COACTIVATOR DCOH AND ITS COMPLEX WITH A PRODUCT ANALOGUE. PROTEIN SCI. V. 5 1963 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HBI A:105;
B:105;
C:105;
D:105;
E:105;
F:105;
G:105;
H:105;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
239.231 C9 H13 N5 O3 C[C@@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1DCP 2.3 Å EC: 4.2.1.96 DCOH, A BIFUNCTIONAL PROTEIN-BINDING TRANSCRIPTIONAL COACTIVATOR, COMPLEXED WITH BIOPTERIN RATTUS NORVEGICUS TRANSCRIPTIONAL STIMULATOR DIMERIZATION COFACTOR DEHYDRATASE 4A-CARBINOLAMINE DEHYDRATASE TRANSREGULATOR OF HOMEODOMAIN PROTEINS
Ref.: HIGH-RESOLUTION STRUCTURES OF THE BIFUNCTIONAL ENZYME AND TRANSCRIPTIONAL COACTIVATOR DCOH AND ITS COMPLEX WITH A PRODUCT ANALOGUE. PROTEIN SCI. V. 5 1963 1996
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1DCP - HBI C9 H13 N5 O3 C[C@@H]([C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1DCP - HBI C9 H13 N5 O3 C[C@@H]([C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1DCP - HBI C9 H13 N5 O3 C[C@@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HBI; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 HBI 1 1
2 44W 0.519231 0.816667
3 PH2 0.464286 0.852459
4 ZSP 0.45 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 113
This union binding pocket(no: 1) in the query (biounit: 1dcp.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 5Y5Q DUT None
2 1O7Q UDP None
3 3NKV GNP None
4 6HOY AR6 None
5 6HOY TSN None
6 2ZWI C5P None
7 4A34 FUL None
8 1O44 852 None
9 1V0O INR None
10 2FWP CIT None
11 3AB1 FAD None
12 3D04 SAK None
13 1Z06 GNP 1.92308
14 2Y6Q I7T 1.92308
15 2Y6Q FAD 1.92308
16 1T7Q 152 1.92308
17 1T7Q COA 1.92308
18 3T31 DCQ 1.92308
19 3T31 FAD 1.92308
20 1YKJ FAD 2.88462
21 4MCC 21X 2.88462
22 3CGD NAD 2.88462
23 3CGD FAD 2.88462
24 3CGD COA 2.88462
25 3ZRM ZRM 2.88462
26 1EBG PAH 2.88462
27 1A5Z NAD 2.88462
28 2IHK CSF 3.84615
29 1ZEA DVA DPR GLY DSN DGN DHI DTY DAS DSN 3.84615
30 3OZ2 FAD 3.84615
31 3L9W GSH 3.84615
32 3L9W AMP 3.84615
33 1ZPD DPX 3.84615
34 3GDH MGP 3.84615
35 4K5S FAD 4.80769
36 4K5S PM0 4.80769
37 4C3Y FAD 4.80769
38 1R18 SAH 4.80769
39 4C3Y ANB 4.80769
40 4N9I PCG 5.76923
41 4YVZ 3AT 5.76923
42 4UOX PUT 5.76923
43 5JCP GDP ALF 5.76923
44 4UOX PLP PUT 5.76923
45 4X9M FAD 5.76923
46 5OGX FAD 5.76923
47 2BVL UDP 5.76923
48 2BVL GLC 5.76923
49 3LKZ SFG 5.76923
50 1JQY A32 5.82524
51 5KOX RFP 6.73077
52 5KOX FAD 6.73077
53 5BUK FAD 6.73077
54 3NYC FAD 6.73077
55 3NYC IAR 6.73077
56 1YQZ FAD 6.73077
57 4BJZ P3A 6.73077
58 4BJZ FAD 6.73077
59 5VN0 FAD 6.73077
60 5G4J EXT 6.73077
61 1S8F GDP 6.73077
62 4TXI FAD 6.73077
63 5Y77 FAD 6.73077
64 5UWI GNP 6.73077
65 5VN0 NAI 6.73077
66 6AIN FAD 7.69231
67 4CFU 2WC 7.69231
68 4EIP FAD 7.69231
69 4USR FAD 7.69231
70 1KPG SAH 7.69231
71 1FUR MLT 7.69231
72 3E1T FAD 8.65385
73 1GTE FAD 8.65385
74 2RGJ FAD 8.65385
75 5GSN FAD 8.65385
76 5SZH GNP 8.65385
77 2R4J FAD 8.65385
78 2R4J 13P 8.65385
79 1UWK URO 9.61539
80 1UWK NAD 9.61539
81 2F1K NAP 9.61539
82 2QA1 FAD 9.61539
83 4X5S AZM 9.61539
84 5ZZ6 NAD 9.61539
85 2CDU FAD 9.61539
86 1Z0K GTP 10.5769
87 6AU6 GDP 10.5769
88 4U03 GTP 10.5769
89 4U03 TLL 10.5769
90 1E8G FCR 10.5769
91 2BME GNP 10.5769
92 5X68 FAD 10.5769
93 4G2R H1L 11.5385
94 2RGO FAD 11.5385
95 1LSH PLD 11.5385
96 4LHW GNP 11.5385
97 3O7J 2AL 12.5
98 1NST A3P 13.4615
99 1CKM GTP 13.4615
100 4MZQ 1VU 13.4615
101 2QTR NXX 14.4231
102 5ODQ FAD 15.3846
103 4V3C C 16.3462
104 1X87 NAD 16.3462
105 2ZFZ ARG 16.4557
106 5GQX GLC GLC GLC GLC 17.3077
107 1YBH FAD 18.2692
108 5HXI 5HN 19.2308
109 5HXI FAD 19.2308
110 5ITZ GTP 20.1923
111 4NES UD1 21.1538
112 6C1S EFV 25
113 2Z4T C5P 34.6154
Pocket No.: 2; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 159
This union binding pocket(no: 2) in the query (biounit: 1dcp.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5N6C NAD None
2 2FWP ICR None
3 3OU2 SAH None
4 5WUW NAP None
5 5N53 8NB None
6 1IYB 5GP None
7 6EQS BV8 None
8 4CQM NAP None
9 5MW8 ATP None
10 4R74 F6P None
11 2EW1 GNP None
12 6GFK SAH None
13 4YT4 FE9 None
14 6EJI UD2 1.92308
15 5EIN NAP 1.92308
16 4B7X NAP 2.88462
17 2ZB3 NDP 2.88462
18 1G0N NDP 2.88462
19 1G0N PHH 2.88462
20 1UM0 FMN 2.88462
21 1TDF FAD 2.88462
22 1HEX NAD 2.88462
23 3JYN NDP 2.88462
24 3QWI CUE 2.88462
25 3QWI NAP 2.88462
26 5I7A 68Q 2.88462
27 1P7L SAM 3.84615
28 1P7L PPK 3.84615
29 2PT9 S4M 3.84615
30 1P7L ANP 3.84615
31 1GSA GSH 3.84615
32 2PT9 2MH 3.84615
33 4EUU BX7 3.84615
34 1YVD GNP 3.84615
35 2Q4H AMP 3.84615
36 6DNT NAD 3.84615
37 1FFU CDP 4.80769
38 3FC4 EDO 4.80769
39 5Y6Q MCN 4.80769
40 4MS4 2C0 4.80769
41 2D4V NAD 4.80769
42 1YY5 FAD 4.80769
43 4BV6 FAD 4.80769
44 6F7L FAD 4.80769
45 1JQ3 AAT 5.76923
46 2I7C AAT 5.76923
47 1XFF GLU 5.76923
48 5L95 AMP 5.76923
49 1PVN MZP 5.76923
50 5N5S NAP 5.76923
51 3NKS FAD 5.76923
52 4I4Z 2NE 5.76923
53 2GKS ADP 6.73077
54 5WGR FAD 6.73077
55 3H4V NAP 6.73077
56 4R98 GNH 6.73077
57 2HMT NAI 6.73077
58 1EK0 GNP 6.73077
59 1Y3A GDP 6.73077
60 2OM2 GDP 6.73077
61 3FXU TSU 6.73077
62 1UH4 BGC BGC GLC 7.69231
63 1EU1 MGD 7.69231
64 2IVD FAD 7.69231
65 2PHT MAN MAN MAN 7.69231
66 1Q8P MAN MMA 7.69231
67 1QMG APX 7.69231
68 4HSU FAD 7.69231
69 4FWE FAD 7.69231
70 2PHW MAN MAN 7.69231
71 4GUT FAD 7.69231
72 2PHX MAN MAN 7.69231
73 2PHR MAN MAN 7.69231
74 1Q8Q MAN MMA 7.69231
75 4GUS FAD 7.69231
76 2PHF MAN MAN 7.69231
77 5KDO GDP 7.69231
78 1UKG MMA 7.69231
79 2PHW MAN MAN MAN BMA MAN MAN MAN 7.69231
80 1Q8O MAN MMA 7.69231
81 1Q8V MAN MAN 7.69231
82 2PHU MAN MAN 7.69231
83 2PHU MAN MAN MAN BMA MAN 7.69231
84 1Q8S MAN MMA 7.69231
85 2PHT MAN MAN MAN BMA MAN 7.69231
86 4XSU UDP 7.69231
87 4XSU GLC 7.69231
88 1TMO 2MD 8.65385
89 5MBX FAD 8.65385
90 5MBX SP5 8.65385
91 3KLJ FAD 8.65385
92 5VKT NAP 8.65385
93 1BVY FMN 8.65385
94 4CME NAP 8.65385
95 3JQF NAP 8.65385
96 2XCG XCG 8.65385
97 2BD0 NAP 8.65385
98 1RF6 S3P 8.65385
99 1KQF MGD 8.65385
100 2NU8 COA 8.65385
101 4CM9 NAP 8.65385
102 5K6A NAP 8.65385
103 4CM4 NAP 8.65385
104 1VD3 U2P 9.61539
105 4MAF ADX 9.61539
106 2WTX VDO 9.61539
107 2WTX UDP 9.61539
108 1X7D NAD 9.61539
109 1X7D ORN 9.61539
110 1J0D 5PA 9.61539
111 4YNM SAM 10.5769
112 1RJW ETF 10.5769
113 4F97 VDO 10.5769
114 3C6K SPD 10.5769
115 3C6K MTA 10.5769
116 4R3U 3HC 10.5769
117 5WC2 ADP 10.5769
118 1A4R GDP 11.5385
119 5THQ NDP 11.5385
120 3DZ6 M8E 11.5385
121 3QBT GNP 11.5385
122 1RJD SAM 11.5385
123 1TZJ A3B 11.5385
124 1R27 MGD 12.5
125 2VBU CDP 12.5
126 1RM6 PCD 13.4615
127 5G5G MCN 13.4615
128 1N62 MCN 13.4615
129 2NSJ C2R 13.4615
130 1T3Q MCN 14.4231
131 2O07 MTA 14.4231
132 2O07 SPD 14.4231
133 3G5D 1N1 14.4231
134 3CX8 GSP 15.3846
135 2IVF MD1 16.3462
136 1TU3 GNP 16.3462
137 1UCD U5P 17.3077
138 1UCD URA 17.3077
139 3GRU AMP 17.3077
140 4UP3 FAD 17.3077
141 2X7J TPP 17.3077
142 6FL8 TIY 19.2308
143 6FL8 ADP 19.2308
144 1RSG FAD 19.2308
145 4CNK FAD 19.2308
146 3UDZ ADP 19.2308
147 1DEK DGP 19.2308
148 4XYM A12 21.1538
149 5XGX DAS DLY 23.0769
150 1GP2 GDP 23.0769
151 6CRK GDP 23.0769
152 1GOT GDP 23.0769
153 1ZCB GDP 25
154 3AB3 GDP 25
155 1FQK GDP 25
156 3HRD MCN 25
157 2XTZ GSP 30.7692
158 1AOE NDP 34.6154
159 1AOE GW3 34.6154
Pocket No.: 3; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 178
This union binding pocket(no: 3) in the query (biounit: 1dcp.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 1U7Z PMT None
2 3U7S 017 None
3 1Z0A GDP None
4 4U0W 16G None
5 4YUW S4M None
6 4YUW 4JU None
7 4B8V NDG NAG NAG NAG None
8 1YZQ GNP None
9 2XB8 XNW None
10 3GGU 017 None
11 3A4T SFG None
12 1VG8 GNP None
13 4Z87 5GP None
14 2UXR ICT None
15 5WDR GNP None
16 1NBU PH2 None
17 3NWQ 2NC None
18 3MWS 017 None
19 4LRZ ADP None
20 1YZG GDP None
21 4XUC 43G None
22 4XUC SAM None
23 1MKY GDP 1.92308
24 1MH1 GNP 2.88462
25 3SBD GNP 2.88462
26 3TKL GTP 2.88462
27 1LFD GNP 2.88462
28 2ZB4 5OP 2.88462
29 2ZB4 NAP 2.88462
30 1Z0J GTP 3.84615
31 2FFQ GSP 3.84615
32 1WMA NDP 3.84615
33 1WMA AB3 3.84615
34 5M58 SAH 3.84615
35 5MGZ SAH 3.84615
36 1RQL VSO 3.84615
37 3GDH SAH 3.84615
38 2AF6 BRU 4.26357
39 1Y8Q ATP 4.80769
40 1LVL FAD 4.80769
41 2QZZ EMF 4.80769
42 2QZZ NAP 4.80769
43 5IL1 SAM 4.80769
44 4NEC SAH 4.80769
45 2YVF FAD 5.76923
46 2YVF NAD 5.76923
47 2CFD R4A 5.76923
48 2VN9 GVD 5.76923
49 6BCA GSP 5.76923
50 6BCB GSP 5.76923
51 1IBR GNP 5.76923
52 2GCO GNP 5.76923
53 3DMH GMP 5.76923
54 3DMH SAM 5.76923
55 4XSH GSP 5.76923
56 1YB5 NAP 5.76923
57 3NTD FAD 5.76923
58 4NTM 2K8 5.76923
59 5YFT RI2 5.76923
60 3BEO UD1 5.76923
61 3IWD M2T 5.88235
62 5ZZO FLC 6.73077
63 6E8I PTR 6.73077
64 1LCK GLU GLY GLN PTR GLN PRO GLN PRO ALA 6.73077
65 5UWP GNP 6.73077
66 1TAD ALF 6.73077
67 1TAD GDP 6.73077
68 5FJN FAD 6.73077
69 5FJN BE2 6.73077
70 5DIF GNP 6.73077
71 5UWU GNP 6.73077
72 6CIT GNP 6.73077
73 5UWR GNP 6.73077
74 4HAT GNP 6.73077
75 5UWW GNP 6.73077
76 3TPV ADE 6.73077
77 5UWT GNP 6.73077
78 5UWO GNP 6.73077
79 5UWJ GNP 6.73077
80 5DI9 GNP 6.73077
81 5DHF GNP 6.73077
82 5EZ7 FAD 6.73077
83 2BRY FAD 6.73077
84 5UWS GNP 6.73077
85 4J7U YTZ 6.73077
86 4J7U NAP 6.73077
87 4AMV F6R 6.73077
88 1ZJ6 G3D 6.73077
89 1KBI FMN 6.73077
90 4UUW AMP 6.73077
91 5UWQ GNP 6.73077
92 2XVM SAH 6.73077
93 1L6O SER LEU LYS LEU MET THR THR VAL 7.36842
94 3GD4 NAD 7.69231
95 3GD4 FAD 7.69231
96 4NTC FAD 7.69231
97 5KJK 6T1 7.69231
98 5KJK SAM 7.69231
99 1TX4 ALF GDP 7.69231
100 2XVF FAD 7.69231
101 2JAJ D20 7.69231
102 1YZN GNP 7.69231
103 1DMR PGD 7.69231
104 4NON GDP 7.69231
105 5K0A FAD 7.69231
106 5O74 GDP 7.69231
107 3WCS MAN NAG GAL 7.69231
108 4USI ATP 7.69231
109 4O9S 2RY 7.69231
110 5BRT FAD 7.69231
111 5BRT CH9 7.69231
112 3S5W FAD 7.69231
113 6BC0 GSP 7.69231
114 2C6Q NDP 8.65385
115 1HE1 AF3 8.65385
116 1WA5 GTP 8.65385
117 3N8K D1X 8.65385
118 4JGP PYR 8.65385
119 3SMA ACO 8.65385
120 1PN0 FAD 8.65385
121 1PN0 IPH 8.65385
122 4YSX FAD 8.65385
123 1NVV GNP 8.65385
124 1N07 ADP 8.65385
125 1N07 FMN 8.65385
126 5THZ SAH 8.65385
127 2ICY UPG 8.65385
128 5THY SAH 8.65385
129 4DM8 REA 8.65385
130 3N0S ACO 9.61539
131 6BQ6 TER 9.61539
132 3HB5 NAP 9.61539
133 2VHW NAI 9.61539
134 1HK8 DGT 9.61539
135 2XTN GTP 9.61539
136 1KOJ PAN 10.5769
137 5MJI 7O6 10.5769
138 3RHZ UDP 10.5769
139 2O2C G6Q 10.5769
140 5WS9 AMP 10.5769
141 1DKU AP2 10.5769
142 2YVJ NAI 10.5769
143 1ON3 MCA 10.5769
144 3TW1 AHN 10.5769
145 5BVA FAD 11.5385
146 2NGR AF3 11.5385
147 1GRN AF3 11.5385
148 2WMO GTP 11.5385
149 3RNM FAD 11.5385
150 1VL8 NAP 11.5385
151 1CY2 TMP 11.5385
152 3TNF GNP 11.5385
153 5I39 FAD 11.5385
154 1A4R GNH 11.5385
155 4K81 GTP 11.5385
156 4YLG GDP 12.5
157 2CXS F6P 12.5
158 1R4A GNP 12.5
159 1G4U AF3 12.5
160 4LX0 BEF GDP 13.4615
161 6D6Y SAH 14.4231
162 4MRT COA 14.4231
163 5KF6 FAD 14.4231
164 3DNT ATP 15.3846
165 2F5Z FAD 15.3846
166 2P2V CSF 15.3846
167 1WQ1 AF3 16.3462
168 3KV8 FAH 18.2692
169 3GMB FAD 19.2308
170 2ZE3 AKG 20.1923
171 4XYM COA 21.1538
172 1SKQ GDP 21.1538
173 1SVK ALF GDP 23.0769
174 1FQJ GDP 25
175 2FJU GSP 25
176 1GET FAD 25
177 2HQM FAD 29.8077
178 5UWH GNP 31.8182
Pocket No.: 4; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 130
This union binding pocket(no: 4) in the query (biounit: 1dcp.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 3FUU ADN None
2 5WA9 9ZD None
3 1T57 FMN None
4 6C8X BVR None
5 3IUY AMP None
6 6FHO FAD None
7 4ZCC FAD None
8 1UAD GNP None
9 4M8X KGQ None
10 1U8Z GDP None
11 1LSS NAD None
12 2O4N TPV None
13 1DLJ NAI None
14 1DLJ UGA None
15 5JAX 6J7 None
16 4GV8 DUP None
17 2AZC 3TL None
18 1K7T NAG GAL None
19 4R84 CSF 1.92308
20 4JK3 NAD 1.92308
21 3A1S GDP 1.92308
22 2OYS FMN 2.88462
23 3UOY FAD 2.88462
24 3UOY NAP 2.88462
25 3CGB FAD 2.88462
26 5CPR SAM 2.88462
27 1SQS TLA 2.88462
28 5AHO TLA 2.88462
29 1SQF SAM 2.88462
30 5T9E NAP 2.88462
31 6DUB SAH 2.88462
32 5E95 GDP 2.88462
33 5JCM ISD 2.88462
34 5JCM FAD 2.88462
35 1ZEM NAD 2.88462
36 1YKJ PHB 2.88462
37 3DDC GNP 2.88462
38 2C5L GTP 2.88462
39 1Q0H FOM 3.84615
40 5O2T GSP 3.84615
41 5ZI9 FLC 3.84615
42 4ZRN NAD 3.84615
43 3VC1 SAH 4.16667
44 2GJ3 FAD 4.80769
45 3IHG FAD 4.80769
46 4YGF AZM 4.80769
47 4YRY FAD 4.80769
48 1DMY AZM 4.80769
49 5FM0 WAQ 4.80769
50 6H36 FKE 4.80769
51 3GGO NAI 4.80769
52 2POC BG6 4.80769
53 3PT9 SAH 4.80769
54 4HVA 4HV 4.80769
55 4D04 FAD 5.76923
56 4D04 NAP 5.76923
57 1Q9I TEO 5.76923
58 1Q9I FAD 5.76923
59 5AE2 FYC 5.76923
60 5AE2 FAD 5.76923
61 3MQ2 SAH 5.76923
62 2ZJ3 G6P 5.76923
63 1TLL FAD 5.76923
64 1CXZ GSP 5.76923
65 1X9I G6Q 5.76923
66 5TUK FAD 6.73077
67 1GPE FAD 6.73077
68 4IXH IMP 6.73077
69 5MZI FYK 6.73077
70 5MZI FAD 6.73077
71 3H4V DVP 6.73077
72 4H2V AMP 6.73077
73 5G3U ITW 7.69231
74 5G3U FDA 7.69231
75 1EP2 ORO 7.69231
76 4JDR FAD 7.69231
77 4CMI NAP 8.65385
78 5JDC NAP 8.65385
79 4CLR NAP 8.65385
80 2WD7 NAP 8.65385
81 2VZ0 NAP 8.65385
82 2VZ0 D64 8.65385
83 5JCJ NAP 8.65385
84 3JQ7 NAP 8.65385
85 3BMN NAP 8.65385
86 3JQ9 NAP 8.65385
87 4CLO NAP 8.65385
88 4CM8 NAP 8.65385
89 5JDI NAP 8.65385
90 3JQB NAP 8.65385
91 4ZFL 4NK 8.65385
92 3JQ8 NAP 8.65385
93 3JQA NAP 8.65385
94 3QJ4 FAD 8.65385
95 3JQG NAP 8.65385
96 3BMO NAP 8.65385
97 3BMQ NAP 8.65385
98 1RP0 AHZ 9.61539
99 4AP3 FAD 9.61539
100 4AP3 NAP 9.61539
101 5ZZ6 ADP 9.61539
102 3NJ4 NAD 10.5769
103 1MXH DHF 10.5769
104 2YVJ FAD 10.5769
105 1MXH NAP 10.5769
106 4R5M NAP 10.5769
107 4R5M 4NO 10.5769
108 6F97 FAD 10.5769
109 3LXD FAD 11.5385
110 5AZ1 NDP 11.5385
111 1D4D FAD 12.5
112 1ZC3 GNP 12.5
113 3VYW SAM 12.5
114 1NVM NAD 12.5
115 5ZYN FAD 13.4615
116 3OJO NAD 13.4615
117 5TUF FAD 13.4615
118 2FAH GDP 13.4615
119 3B1F NAD 14.4231
120 2WK1 SAH 14.4231
121 4RSL FAD 14.4231
122 4CL6 7SB 15.3846
123 4IPE ANP 16.3462
124 5DY5 5GR 18.2692
125 2E5V FAD 19.2308
126 1WG8 SAM 21.1538
127 6ECW SAH 22.1154
128 3FPZ AHZ 24.0385
129 4PU5 ANP 26.9231
130 1KNR FAD 31.7308
Pocket No.: 5; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 71
This union binding pocket(no: 5) in the query (biounit: 1dcp.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5XC5 GTP None
2 1PNO NAP None
3 3S43 478 None
4 4C12 ADP None
5 2CJW GDP None
6 4YHQ G10 None
7 1IDA 0PO None
8 4DMG SAM None
9 4Q5M ROC None
10 5O3Q CMP None
11 3A27 SAM None
12 5TBS ADE 1.92308
13 5XLX SAH 1.92308
14 3KAP FMN 2.88462
15 5T52 A2G 3.84615
16 5T52 NGA 3.84615
17 4FL3 ANP 3.84615
18 1A5V Y3 4.80769
19 4IPN 1FT 4.80769
20 3HNA SAH 4.80769
21 5T0K SAM 4.80769
22 2RFI SAH 4.80769
23 5JIY SAM 4.80769
24 1OT6 HC4 4.80769
25 3SWC SAH 4.80769
26 3H8V ATP 5.76923
27 4N82 FMN 5.76923
28 5Z6T NAP 5.76923
29 2WEL K88 5.76923
30 1QAN SAH 5.76923
31 5EYG NAP 6.73077
32 4BLW AMP 6.73077
33 1V59 FAD 6.73077
34 4MTI 2DX 6.73077
35 4BLW SAH 6.73077
36 4BMO FMN 7.69231
37 3PGU OLA 7.69231
38 1P1C SAH 7.69231
39 4GOJ GNP 7.69231
40 4ZI2 GNP 7.69231
41 6D5G GNP 8.65385
42 6D55 GNP 8.65385
43 6BVJ GNP 8.65385
44 6D5L GNP 8.65385
45 6BVI GNP 8.65385
46 6D5E GNP 8.65385
47 6D56 GNP 8.65385
48 6BVL GNP 8.65385
49 6D5V GNP 8.65385
50 6D5J GNP 8.65385
51 6D5M GNP 8.65385
52 6BVK GNP 8.65385
53 6D59 GNP 8.65385
54 6D5H GNP 8.65385
55 6BVM GNP 8.65385
56 3WV1 WHH 8.65385
57 3SWG EPZ 9.61539
58 6MJ7 ARG 10.9091
59 5J5Z FAD 11.5385
60 2EFE GNH 11.5385
61 3BBH SFG 11.5385
62 3BBD SAH 11.5385
63 2A9D MTE 12.5
64 1SOX MTE 12.5
65 3T2C 13P 13.4615
66 2RAB FAD 13.4615
67 1R2Q GNP 16.3462
68 3F6R FMN 17.3077
69 5H7K GDP 22.1154
70 4NCN GTP 29.8077
71 3HQP FDP 35.5769
Pocket No.: 6; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 71
This union binding pocket(no: 6) in the query (biounit: 1dcp.bio2) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1Z08 GNP None
2 1TZD ADP None
3 1W2D 4IP None
4 1W2D ADP None
5 3NBC LAT None
6 5H5O PCG None
7 3GQK ATP None
8 3OCP CMP None
9 2WAT COA None
10 4NJS G08 None
11 5D9O BGC BGC BGC BGC 1.92308
12 3A9Y CYS 1.92308
13 1P9P SAH 2.88462
14 3UBM COA 2.88462
15 5CAE SIN 2.88462
16 5CAE COA 2.88462
17 4QVX 3CQ 3.59281
18 4OHU 2TK 3.84615
19 4OHU NAD 3.84615
20 5L4S 6KX 3.84615
21 5L4S NAP 3.84615
22 3A4V PYR 3.84615
23 1N5D NDP 3.84615
24 5L53 NAP 3.84615
25 3A4V NAD 3.84615
26 1P7L MET 3.84615
27 2IF8 ADP 4.80769
28 3U2U UDP 4.80769
29 6FE1 V14 4.80769
30 1A27 NAP 4.80769
31 3KAL HGS 4.80769
32 5KMS NAD 5.76923
33 5EOB 5QQ 5.76923
34 1QG6 NAD 5.76923
35 1QG6 TCL 5.76923
36 3LL5 ATP 5.76923
37 4NDO ATP 5.76923
38 3C1M ANP 5.76923
39 1SQL GUN 5.76923
40 5X1M DHB 5.76923
41 5MWY YNU 6.73077
42 3MF2 AMP 6.73077
43 4H2W AMP 6.73077
44 4H2X G5A 6.73077
45 1A8R GTP 6.73077
46 1MOQ GLP 6.73077
47 4H2W 5GP 6.73077
48 2G37 FAD 6.73077
49 5W5R PYR 6.73077
50 5BN3 ADP 6.73077
51 1EFV AMP 7.69231
52 4MIX UD1 7.69231
53 3HXU A5A 7.69231
54 3RJ5 NAD 8.65385
55 2CJ9 SSA 8.65385
56 4KS7 X4Z 9.61539
57 4O4F IHP 12.5
58 4O4F ATP 12.5
59 1D4O NAP 12.5
60 3QF7 ANP 13.4615
61 1U8X NAD 16.3462
62 3MJH GTP 16.3462
63 2AG5 NAD 18.2692
64 1T8U A3P 18.2692
65 1T8U UAP SGN IDS SGN 18.2692
66 3RYC GTP 19.2308
67 5EIB GTP 19.2308
68 4W88 GAL BGC BGC BGC XYS XYS 21.1538
69 2NX1 PEP 23.0769
70 2NX1 RP5 23.0769
71 1LL2 UPG 28.8462
Pocket No.: 7; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 40
This union binding pocket(no: 7) in the query (biounit: 1dcp.bio2) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 4BUZ OAD None
2 4BUZ NAD None
3 4BUZ OCZ None
4 4BAS GNP None
5 4C4P GNP None
6 3ZLB ANP None
7 1DUB CAA None
8 2FXD DR7 None
9 3X27 TRP None
10 1GWN GTP 1.92308
11 3REF GDP 1.92308
12 2CJF RP4 1.92308
13 3ZLR X0B 2.88462
14 1CLU DBG 2.88462
15 3WYA GDP 2.88462
16 5JCM NAD 2.88462
17 1XHC FAD 3.84615
18 1QS8 IVA VAL VAL STA ALA STA 5.76923
19 3WYF GTP 6.73077
20 1KPG 16A 7.69231
21 2AKO ADP 8.65385
22 1T36 ORN 8.65385
23 3T3C 017 9.09091
24 2OYH GLY HIS ARG PRO 9.61539
25 4BWL MN9 9.61539
26 5O4J PJL 10.5769
27 5O4J 9KH 10.5769
28 5O4J SAH 10.5769
29 1NY5 ADP 11.5385
30 3N5C GDP 11.5385
31 1MR3 G3D 12.5
32 5GOE GDP 12.5
33 3FSM 2NC 12.5
34 2FH5 GTP 13.4615
35 4EPL JAI 15.3846
36 1EYN 2AN 17.3077
37 1KSH GDP 18.2692
38 4AF0 IMP 20.1923
39 1KQN NAD 25.9615
40 5DI3 GNP 33.6538
Pocket No.: 8; Query (leader) PDB : 1DCP; Ligand: HBI; Similar sites found with APoc: 93
This union binding pocket(no: 8) in the query (biounit: 1dcp.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4RR7 A3S None
2 2YYY NAP None
3 2Q7V FAD None
4 2DT5 NAD None
5 3HVJ 705 None
6 5IBE 69M None
7 5U19 SAH None
8 5U19 827 None
9 3EHG ATP None
10 5E8J SAH None
11 3L8G GMB None
12 4BQS K2Q None
13 2GL0 ADN None
14 1PZ4 PLM None
15 3PD2 A3S 1.92308
16 4B63 FAD 1.92308
17 4B63 ORN 1.92308
18 4B63 NAP 1.92308
19 5N5D SAM 1.92308
20 3NTA FAD 1.92308
21 4POO SAM 1.92308
22 5U8U FAD 2.88462
23 1ZK7 FAD 2.88462
24 3ICS FAD 3.84615
25 3ICT FAD 3.84615
26 1WY7 SAH 3.84615
27 3ICR FAD 3.84615
28 1CF2 NAP 4.80769
29 4DI8 0GZ 4.80769
30 4DI8 0GY 4.80769
31 3CTY FAD 4.80769
32 6CEN SAM 4.80769
33 4GID 0GH 4.80769
34 3VCY UD1 4.80769
35 1F20 FAD 4.80769
36 3SIG AR6 5.76923
37 1MI3 NAD 5.76923
38 5Z2F NAP 5.76923
39 5N0J FAD 5.76923
40 3A25 SAM 5.76923
41 1TD2 PXL 5.76923
42 1PZ1 NAP 6.73077
43 1BH2 GSP 6.73077
44 3M1I GTP 6.73077
45 5BVE 4VG 6.73077
46 4U9U FAD 6.73077
47 3AFN NAP 6.73077
48 4I54 1C1 6.73077
49 1V8B NAD 6.73077
50 5EYY MDM 7.69231
51 2AUY NAG MAN MMA 7.69231
52 2PHX MAN MAN MAN MAN 7.69231
53 2AR6 NAG MAN MAN MAN NAG 7.69231
54 1EP2 FMN 7.69231
55 2PHR MAN MAN BMA MAN 7.69231
56 1Q8V MAN MAN MAN 7.69231
57 2GND MAN MMA 7.69231
58 3WYG GTP 7.89474
59 1QXO EPS 8.65385
60 2O4C NAD 8.65385
61 3OZV FAD 8.65385
62 3BAZ NAP 8.65385
63 2CJA ATP 8.65385
64 3FPF TNA 9.61539
65 3FPF MTA 9.61539
66 2NPX FAD 9.61539
67 4PVD NDP 9.61539
68 1E6E FAD 9.61539
69 3DRW AMP 9.61539
70 1MDZ DCS 10.5769
71 1MDZ PLP 10.5769
72 3GJX GTP 11.5385
73 5O2Z FLC 11.5385
74 4PIV NDP 11.5385
75 5V22 SAH 11.5385
76 5JLB SAH 11.5385
77 5LU5 M7P 11.5385
78 5NMX FAD 11.5385
79 1PJS NAD 12.5
80 2RAB NAD 13.4615
81 5JCA NDP 13.4615
82 5JCA FAD 13.4615
83 1QO8 FAD 14.4231
84 4TM3 FAD 15.3846
85 4P86 5GP 15.3846
86 5WKC FAD 16.3462
87 1T9D FAD 16.3462
88 4ZKD GDP 19.2308
89 1GET NAP 25
90 3LAD FAD 25
91 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 27.8846
92 3ZYR NAG NAG BMA MAN MAN NAG NAG 27.8846
93 4TMZ GSP 29.8077
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