Receptor
PDB id Resolution Class Description Source Keywords
1DBP 2.2 Å NON-ENZYME: TRANSPORT IDENTICAL MUTATIONS AT CORRESPONDING POSITIONS IN TWO HOMOLOGOUS PROTEINS WITH NON-IDENTICAL EFFECTS ESCHERICHIA COLI BINDING PROTEIN
Ref.: IDENTICAL MUTATIONS AT CORRESPONDING POSITIONS IN TWO HOMOLOGOUS PROTEINS WITH NONIDENTICAL EFFECTS. J.BIOL.CHEM. V. 269 11196 1994
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
RIP A:272;
Valid;
none;
submit data
150.13 C5 H10 O5 C1[C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1DRJ 2.5 Å NON-ENZYME: TRANSPORT PROBING PROTEIN-PROTEIN INTERACTIONS: THE RIBOSE-BINDING PROTEIN IN BACTERIAL TRANSPORT AND CHEMOTAXIS ESCHERICHIA COLI SUGAR TRANSPORT
Ref.: PROBING PROTEIN-PROTEIN INTERACTIONS. THE RIBOSE-BINDING PROTEIN IN BACTERIAL TRANSPORT AND CHEMOTAXIS. J.BIOL.CHEM. V. 269 30206 1994
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 1DBP - RIP C5 H10 O5 C1[C@H]([C....
2 2DRI Kd = 0.13 uM RIP C5 H10 O5 C1[C@H]([C....
3 1DRK Kd = 0.15 uM RIP C5 H10 O5 C1[C@H]([C....
4 1DRJ Kd = 0.04 uM RIP C5 H10 O5 C1[C@H]([C....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 1DBP - RIP C5 H10 O5 C1[C@H]([C....
2 2DRI Kd = 0.13 uM RIP C5 H10 O5 C1[C@H]([C....
3 1DRK Kd = 0.15 uM RIP C5 H10 O5 C1[C@H]([C....
4 1DRJ Kd = 0.04 uM RIP C5 H10 O5 C1[C@H]([C....
5 2IOY - RIP C5 H10 O5 C1[C@H]([C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 141 families.
1 1DBP - RIP C5 H10 O5 C1[C@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: RIP; Similar ligands found: 14
No: Ligand ECFP6 Tc MDL keys Tc
1 XYP 1 1
2 0MK 1 1
3 RIP 1 1
4 LXC 1 1
5 ARA 1 1
6 ARB 1 1
7 XYS 1 1
8 HSY 1 1
9 BXP 0.414634 0.84375
10 XYP XYP 0.414634 0.84375
11 XYS XYP 0.414634 0.84375
12 XYS XYS 0.414634 0.84375
13 XYP XYS 0.414634 0.84375
14 FU4 0.4 0.896552
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1DRJ; Ligand: RIP; Similar sites found: 33
This union binding pocket(no: 1) in the query (biounit: 1drj.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3S43 478 0.03052 0.41153 None
2 4ELG 52J 0.0311 0.40024 1.20482
3 5L7G 6QE 0.005579 0.43853 1.84502
4 2A3I C0R 0.01648 0.41275 1.97628
5 5M67 ADE 0.03272 0.42177 2.95203
6 1YNH SUO 0.02255 0.41297 2.95203
7 1LBT T80 0.02382 0.40042 3.32103
8 3AKK ADP 0.01477 0.40609 3.69004
9 4CYI ATP 0.004417 0.44098 4.05904
10 2ZX7 ZX7 0.01562 0.41476 4.05904
11 4LH7 NMN 0.009136 0.40898 4.05904
12 4JR7 GNP 0.01431 0.40776 4.05904
13 3SI2 PBD 0.01813 0.40399 4.79705
14 4HN1 TYD 0.02113 0.40101 4.97512
15 5JO1 6LM 0.01583 0.41524 5.53506
16 1SO0 GAL 0.007718 0.41119 5.90406
17 3JRS A8S 0.0142 0.41397 6.25
18 3KF3 FRU 0.009829 0.43162 6.64207
19 3QXV MTX 0.0226 0.40013 7.14286
20 4UOH ADP 0.0137 0.40392 7.28477
21 5W10 CMP 0.01906 0.40783 8.71795
22 4W97 UCA 0.03177 0.43041 11.5
23 4MLN ODV 0.008204 0.41232 11.7347
24 3CXO 1N5 0.01113 0.40831 12.1771
25 5LE1 6UW 0.009023 0.4011 14.6617
26 2GBB CIT 0.01188 0.40454 16.0256
27 9ABP GLA 0.00002868 0.55005 34.6863
28 9ABP GAL 0.00002868 0.55005 34.6863
29 3O75 F1X 0.0000002449 0.65524 36.3971
30 3MA0 XYP 0.00002133 0.50442 36.9004
31 2GBP BGC 0.000009101 0.57388 37.2694
32 5XSS XYP 0.00001075 0.55286 42.8044
33 2P9H IPT 0.00002516 0.54327 44.6097
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