Receptor
PDB id Resolution Class Description Source Keywords
1CKN 2.5 Å EC: 2.7.7.50 STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP PARAMECIUM BURSARIA CHLORELLA VIRUS 1 MRNA CAPPING ENZYME NUCLEOTIDYLTRANSFERASE
Ref.: X-RAY CRYSTALLOGRAPHY REVEALS A LARGE CONFORMATIONAL CHANGE DURING GUANYL TRANSFER BY MRNA CAPPING ENZYMES. CELL(CAMBRIDGE,MASS.) V. 89 545 1997
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:899;
Valid;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MN B:1001;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
SO4 B:1000;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1CKN 2.5 Å EC: 2.7.7.50 STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP PARAMECIUM BURSARIA CHLORELLA VIRUS 1 MRNA CAPPING ENZYME NUCLEOTIDYLTRANSFERASE
Ref.: X-RAY CRYSTALLOGRAPHY REVEALS A LARGE CONFORMATIONAL CHANGE DURING GUANYL TRANSFER BY MRNA CAPPING ENZYMES. CELL(CAMBRIDGE,MASS.) V. 89 545 1997
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1CKN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1CKN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1CKN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1CKN; Ligand: GTP; Similar sites found: 439
This union binding pocket(no: 1) in the query (biounit: 1ckn.bio4) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1BTN I3P 0.004601 0.45107 None
2 1UO4 PIH 0.003316 0.45 None
3 3BLI ACO 0.005216 0.41332 1.21212
4 2OI2 DP6 0.0005364 0.4376 1.36986
5 4I71 AGV 0.001449 0.43016 1.51515
6 3ZY6 GFB 0.002286 0.42613 1.51515
7 4QVH FLC 0.01664 0.42596 1.51515
8 2PWY SAH 0.0009605 0.44516 1.55039
9 2YLD CMO 0.0006997 0.44747 1.5748
10 4O1M NAD 0.00513 0.42408 1.5873
11 1IOW PHY 0.01194 0.43109 1.63399
12 3SHR CMP 0.002148 0.40085 1.67224
13 2BGM NAJ 0.02183 0.41937 1.79856
14 2BGM MAX 0.01236 0.40108 1.79856
15 3IHB TRS 0.0008057 0.51116 1.81818
16 9LDB OXM 0.001003 0.47612 1.81818
17 9LDT OXM 0.00319 0.45085 1.81818
18 4R33 SAH 0.003419 0.43541 1.81818
19 4R33 TRP 0.003419 0.43541 1.81818
20 3ZRM ZRM 0.005189 0.42838 1.81818
21 1Z45 GAL 0.0009926 0.42761 1.81818
22 4LWA Q13 0.01206 0.41821 1.81818
23 3IHB GLU 0.005465 0.41592 1.81818
24 4IVG ANP 0.02172 0.41526 1.81818
25 1PL6 572 0.0101 0.41523 1.81818
26 1PL6 NAD 0.004685 0.41523 1.81818
27 1GJW GLC 0.005699 0.41512 1.81818
28 8CAT NDP 0.008527 0.40291 1.81818
29 4HA6 PXM 0.006756 0.4 1.81818
30 1JA9 PYQ 0.001611 0.44393 1.82482
31 1JA9 NDP 0.03883 0.41366 1.82482
32 1T8U UAP SGN IDS SGN 0.02183 0.4059 1.83824
33 2Q3M MLA 0.005584 0.43007 1.84049
34 2XK9 XK9 0.01562 0.42605 1.86335
35 1YOE RIB 0.006233 0.41917 1.86335
36 2AEB ABH 0.006793 0.41336 1.86335
37 2HFK E4H 0.0005627 0.43732 1.88088
38 1T3D CYS 0.004855 0.41819 2.07612
39 4F9C 0SX 0.01127 0.40976 2.08333
40 4AZW ATP 0.0009437 0.4691 2.12121
41 3CXO 3LR 0.00106 0.45158 2.12121
42 1XHL NDP 0.002525 0.43978 2.12121
43 2C7G FAD 0.0103 0.43368 2.12121
44 1ZFJ IMP 0.02557 0.43285 2.12121
45 1PEA ACM 0.003871 0.42974 2.12121
46 2C7G ODP 0.01377 0.4272 2.12121
47 2IMP LAC 0.005632 0.40843 2.12121
48 4UAL 3FV 0.01364 0.40767 2.12121
49 1GPJ CIT 0.006071 0.40765 2.12121
50 2DKH FAD 0.01579 0.40687 2.12121
51 3HZT J60 0.006292 0.40647 2.12121
52 4LIT AKG 0.006097 0.40182 2.12121
53 3DGB MUC 0.001548 0.40153 2.12121
54 4AZT LY2 0.01245 0.401 2.12121
55 2Q09 DI6 0.003598 0.40029 2.12121
56 3AKK ADP 0.01478 0.4078 2.15385
57 1TDF FAD 0.00408 0.44554 2.21519
58 1TDF NAP 0.008649 0.44554 2.21519
59 1IYE PGU 0.01262 0.40873 2.26537
60 3RKR NAP 0.0006466 0.43166 2.29008
61 2H6B 3C4 0.01586 0.42438 2.4
62 4DL8 UMP AF3 PO4 0.00566 0.40834 2.41379
63 1I2B USQ 0.00393 0.45204 2.42424
64 1I2B UPG 0.00393 0.45204 2.42424
65 1I2B NAD 0.00393 0.45204 2.42424
66 1Q3Q ANP 0.004351 0.45153 2.42424
67 4NES UDP 0.0005185 0.44575 2.42424
68 3TFC PEP 0.0006364 0.43522 2.42424
69 1KOL NAD 0.007695 0.42367 2.42424
70 1P72 THM 0.00129 0.42312 2.42424
71 4AQL TXC 0.002226 0.4206 2.42424
72 1KBJ FMN 0.006285 0.41477 2.42424
73 1B5E DCM 0.001815 0.41161 2.43902
74 2YK7 CSF 0.001798 0.42843 2.45399
75 4DVE BTN 0.001305 0.41993 2.52525
76 2ZE3 AKG 0.001982 0.42179 2.54545
77 1ZUW DGL 0.002363 0.40725 2.57353
78 1V2X SAM 0.004066 0.41414 2.57732
79 3OIG IMJ 0.001758 0.44779 2.63158
80 1U7Z PMT 0.002741 0.43953 2.65487
81 3ZLM ANP 0.005086 0.40831 2.65957
82 5YAS FAC 0.002752 0.40746 2.72374
83 2Z9V PXM 0.0001558 0.45931 2.72727
84 3UH0 TSB 0.002254 0.42996 2.72727
85 2FFC U5P 0.006417 0.4258 2.72727
86 2YIV NBN 0.004677 0.41891 2.72727
87 2ZJ5 ADP 0.002614 0.41688 2.72727
88 3Q3C NAD 0.02275 0.4158 2.72727
89 1RYD GLC 0.00463 0.41265 2.72727
90 1E4E ADP 0.01183 0.41262 2.72727
91 3UDZ ADP 0.01495 0.40755 2.72727
92 4HZX G39 0.02164 0.40701 2.72727
93 2YIV YIV 0.01288 0.40569 2.72727
94 1WHT BZS 0.005803 0.40848 2.73438
95 1DL7 NCH 0.01461 0.42614 2.75229
96 4LH7 1X8 0.0002226 0.49006 2.78638
97 1NN5 ANP 0.001512 0.44653 2.7907
98 1NN5 2DT 0.001512 0.44653 2.7907
99 3QDY CBS 0.001147 0.44585 2.7972
100 3QDW NDG 0.001458 0.44125 2.7972
101 3QDW A2G 0.006346 0.42739 2.7972
102 3QDY A2G GAL 0.007098 0.41762 2.7972
103 3QDT A2G GAL 0.01323 0.40514 2.7972
104 3QDX CBS 0.0004421 0.40025 2.7972
105 1S68 AMP 0.000005243 0.54803 2.81124
106 1B9I PXG 0.0002854 0.46678 2.83505
107 3U4C NDP 0.004138 0.42667 2.84698
108 2OYS FMN 0.001133 0.4385 2.89256
109 1UAY ADN 0.0005983 0.40534 2.89256
110 1V1A KDG 0.005715 0.40908 2.91262
111 1V1A ADP 0.01512 0.40291 2.91262
112 1UWZ THU 0.003548 0.4104 2.94118
113 4C0X AQN 0.001351 0.45 2.95567
114 4C0X FMN 0.001941 0.43753 2.95567
115 1OIK C26 0.006423 0.40021 2.99003
116 1RYI GOA 0.001826 0.48241 3.0303
117 1R37 NAD 0.000396 0.47686 3.0303
118 4OCV ANP 0.002411 0.44685 3.0303
119 1XMV ADP 0.009695 0.43191 3.0303
120 2HGS ADP 0.008143 0.42597 3.0303
121 1DXY COI 0.008323 0.42172 3.0303
122 2R7K AMZ 0.01451 0.42054 3.0303
123 1RY2 AMP 0.004789 0.41968 3.0303
124 1R37 ETX 0.0003407 0.41875 3.0303
125 1WVG CXY 0.004219 0.41709 3.0303
126 3FED BIX 0.00287 0.41621 3.0303
127 1WVG APR 0.006385 0.41448 3.0303
128 4NST ADP 0.01311 0.40851 3.0303
129 4H3P ANP 0.01368 0.4076 3.0303
130 1UBY DMA 0.00653 0.40199 3.0303
131 3TXO 07U 0.01481 0.40186 3.0303
132 4DYO SD4 0.003427 0.40109 3.0303
133 4BI7 PGA 0.0003869 0.43718 3.11284
134 1PFK ADP 0.001065 0.43103 3.125
135 1Y7P RIP 0.008539 0.41392 3.13901
136 1GSA GSH 0.002613 0.44941 3.16456
137 1GSA ADP 0.009456 0.43002 3.16456
138 1UXG NAD 0.005301 0.43284 3.23625
139 1UXG FUM 0.005301 0.43284 3.23625
140 3U1T MLI 0.004777 0.4185 3.23625
141 3GEG NAD 0.01506 0.40169 3.23887
142 3MAG 3MA 0.01369 0.41896 3.25733
143 2P69 PLP 0.001636 0.42519 3.26797
144 2FWP CIT 0.01479 0.40577 3.27869
145 2FWP ICR 0.02304 0.4019 3.27869
146 3TKA CTN 0.0005948 0.51017 3.33333
147 4ANW O92 0.002562 0.46349 3.33333
148 1VDC FAD 0.001758 0.4628 3.33333
149 2BLE 5GP 0.00339 0.45796 3.33333
150 4OCJ NDG 0.004572 0.45641 3.33333
151 3PNL ADP 0.000687 0.44926 3.33333
152 3ZPG 5GP 0.006099 0.42822 3.33333
153 4G1V FAD 0.004846 0.42239 3.33333
154 4W6Z ETF 0.008176 0.41479 3.33333
155 4GLL NAD 0.04159 0.40139 3.33333
156 3H22 B53 0.002966 0.40621 3.367
157 1XK5 TPG 0.001469 0.45536 3.43137
158 1NW5 SAM 0.003632 0.41612 3.44828
159 1OFH ADP 0.009685 0.40695 3.44828
160 1G8S MET 0.002192 0.42643 3.47826
161 2WGC SIA GAL BGC 0.004439 0.45358 3.50877
162 1WGC SIA GAL BGC 0.008189 0.43023 3.50877
163 2OFE NAG 0.003686 0.41685 3.52113
164 2OFD NGA 0.004163 0.41461 3.52113
165 2BZ1 TAU 0.00236 0.46809 3.57143
166 1QO0 BMD 0.004801 0.41198 3.57143
167 3MBG FAD 0.007047 0.4127 3.59712
168 1NVU GTP 0.02639 0.41423 3.61446
169 1JGS SAL 0.0136 0.42779 3.62319
170 2ZWS PLM 0.00437 0.45393 3.63636
171 4M5P MLA 0.004179 0.44495 3.63636
172 3P7I P7I 0.0005148 0.43885 3.63636
173 4M5P 23W 0.006096 0.42067 3.63636
174 1CBF SAH 0.0001429 0.41669 3.63636
175 4B7E OGA 0.002972 0.41459 3.63636
176 2J0W ADP 0.003256 0.41403 3.63636
177 4OUC 5ID 0.008512 0.41361 3.63636
178 4M51 BEZ 0.01013 0.4105 3.63636
179 2C5S AMP 0.002817 0.40434 3.63636
180 3CQ5 PMP 0.002954 0.40355 3.63636
181 2OKK ABU 0.01445 0.40338 3.63636
182 2QCS ANP 0.03055 0.40119 3.63636
183 3P3N AKG 0.008657 0.40109 3.63636
184 2V7T SAH 0.008302 0.45381 3.67893
185 4IZY 1J2 0.0009177 0.40768 3.79404
186 1EB9 HBA 0.0004177 0.41869 3.81679
187 1P9P SAH 0.003119 0.42245 3.83142
188 4LSJ LSJ 0.002625 0.4237 3.87597
189 3FHI ANP 0.01523 0.41673 3.8961
190 1YFZ IMP 0.004141 0.4087 3.90244
191 2YDW WSH 0.0003221 0.43041 3.92157
192 4GLW 0XT 0.001532 0.44183 3.93443
193 4LHM AZZ 0.001354 0.42855 3.93939
194 4G17 0VN 0.00493 0.42515 3.93939
195 4M2K PLP 0.0008533 0.4241 3.93939
196 1RZM PEP 0.001252 0.42363 3.93939
197 1FDJ 2FP 0.001371 0.42178 3.93939
198 3R35 4CO 0.001018 0.45522 3.97351
199 4N7C AEF 0.001023 0.44803 3.97727
200 2D37 FMN 0.006721 0.41502 3.97727
201 2D37 NAD 0.007262 0.41502 3.97727
202 3HAV ATP 0.002495 0.41486 4.01338
203 1F7L COA 0.005591 0.42685 4.13223
204 2GJ3 FAD 0.01028 0.4119 4.16667
205 4N02 FNR 0.004697 0.44696 4.20168
206 4AF5 CIT 0.00065 0.44883 4.21053
207 1Y75 NAG 0.0007733 0.42573 4.23729
208 3V1U NAD 0.000761 0.45283 4.24242
209 1Z42 HBA 0.01558 0.42091 4.24242
210 1O9U ADZ 0.004207 0.41878 4.24242
211 4IOK XPO 0.006121 0.41214 4.24242
212 1Z44 NPO 0.02764 0.41136 4.24242
213 1KC7 PPR 0.01214 0.40058 4.24242
214 3PMA SCR 0.004835 0.40048 4.2471
215 3LTW HLZ 0.0005005 0.45364 4.28571
216 2VDJ HSE 0.003548 0.43148 4.31894
217 3BHO B4P 0.008993 0.42818 4.32692
218 3EW2 BTN 0.003365 0.4014 4.44444
219 1H16 PYR 0.00003783 0.52206 4.54545
220 3SCH TB6 0.001176 0.4379 4.54545
221 2XVE FAD 0.02674 0.41783 4.54545
222 3DNT ATP 0.01355 0.41638 4.54545
223 1QF5 GDP 0.03492 0.40437 4.54545
224 1QF5 RPL 0.03492 0.40437 4.54545
225 2QCX PF1 0.005772 0.4028 4.56274
226 3FPZ AHZ 0.04489 0.41471 4.60123
227 3KN5 ANP 0.01072 0.41082 4.61538
228 2J7T 274 0.01779 0.41725 4.63576
229 2Q97 ATP 0.0007748 0.44713 4.65116
230 4PO2 ASN ARG LEU LEU LEU THR GLY 0.0001779 0.47319 4.68085
231 4NTD FAD 0.001592 0.45564 4.70588
232 2DWU DGL 0.001107 0.4198 4.71014
233 3PN1 IVH 0.00001172 0.53198 4.71698
234 2BKK ADP 0.01455 0.40005 4.73373
235 3U5S FAD 0.002699 0.4232 4.7619
236 4JLV ADP 0.02012 0.41448 4.83271
237 3ZGE ASP 0.00007151 0.50937 4.84848
238 4IX4 ADP 0.0009629 0.46866 4.84848
239 3SQG COM 0.00692 0.43392 4.84848
240 1Q8Y ADP 0.006191 0.42845 4.84848
241 3SQG TP7 0.00007942 0.42489 4.84848
242 2HXT EHM 0.002889 0.41163 4.84848
243 3I0O ADP 0.002104 0.4012 4.84848
244 1T57 FMN 0.0005557 0.45302 4.85437
245 2GDZ NAD 0.0018 0.44333 4.86891
246 2HGZ PBF 0.00165 0.43724 4.90196
247 3F81 STT 0.00006673 0.52231 4.91803
248 3BY8 MLT 0.000913 0.45021 4.92958
249 4IS0 1R4 0.003959 0.41822 4.97925
250 2PT9 2MH 0.01045 0.41572 4.98442
251 2PT9 S4M 0.007279 0.41212 4.98442
252 2OX9 GAL NAG FUC 0.00526 0.43538 5
253 3SRV S19 0.008761 0.41513 5.05415
254 3TO7 COA 0.001425 0.45774 5.07246
255 3TY5 ADP 0.00001197 0.50443 5.15152
256 3TY5 ATP 0.00004698 0.50162 5.15152
257 1C0I BE2 0.004035 0.44486 5.15152
258 1C0I FAD 0.004035 0.44486 5.15152
259 2BO4 FLC 0.001828 0.43691 5.15152
260 3CL7 HYN 0.002778 0.4279 5.19481
261 1TUV VK3 0.02289 0.40051 5.26316
262 4GJ3 0XP 0.0133 0.42506 5.29801
263 1ULE GLA GAL NAG 0.01046 0.40985 5.33333
264 2BNE U5P 0.007372 0.42168 5.39419
265 2ALG DAO 0.002845 0.42228 5.43478
266 2ALG HP6 0.002845 0.42228 5.43478
267 3DAG FEG 0.0007497 0.4531 5.45455
268 2XDQ MGX 0.003034 0.4428 5.45455
269 3VOT ADP 0.00196 0.43953 5.45455
270 3JDW ORN 0.0006582 0.43927 5.45455
271 3Q9T FAY 0.004237 0.43709 5.45455
272 3IO3 ADP 0.001007 0.43649 5.45455
273 2FGQ MLT 0.002273 0.42576 5.45455
274 3SXF BK5 0.01532 0.42539 5.45455
275 4FGC PQ0 0.00164 0.42515 5.45455
276 2OZE AGS 0.002961 0.41773 5.45455
277 1M0W ANP 0.007521 0.41622 5.45455
278 3GTD MLI 0.006521 0.40063 5.45455
279 1FIQ MTE 0.0005979 0.46356 5.47945
280 1FIQ SAL 0.000699 0.46356 5.47945
281 1FIQ FAD 0.01664 0.40699 5.47945
282 1JN2 SFP 0.04111 0.42349 5.48523
283 2QDT I38 0.002364 0.41736 5.57621
284 1E7S NAP 0.01485 0.40688 5.60748
285 1YOA FMN 0.002057 0.47124 5.66038
286 2DTX BMA 0.001188 0.4623 5.68182
287 2HW1 FRU 0.001392 0.42806 5.7047
288 2PTZ PAH 0.0003035 0.45253 5.75758
289 2HMT NAI 0.01257 0.42445 5.75758
290 2AMV BIN 0.03974 0.40327 5.75758
291 4F2Q QUS 0.00008984 0.47062 5.81395
292 1O68 KIV 0.001091 0.42599 5.81818
293 3KJI ADP 0.003793 0.40925 5.90551
294 3WCS MAN NAG 0.00317 0.40772 5.90551
295 1OTH PAO 0.002995 0.43661 5.919
296 1R0X ATP 0.01442 0.40857 5.94406
297 3CBG FER 0.001938 0.45215 6.03448
298 3CBG 4FE 0.003955 0.44615 6.03448
299 1GU3 BGC BGC BGC BGC BGC 0.003212 0.40749 6.04027
300 4GYW UDP 0.00344 0.43405 6.06061
301 2QK4 ATP 0.002741 0.42981 6.06061
302 4KCF AKM 0.002516 0.428 6.06061
303 4KCF FMN 0.01145 0.41721 6.06061
304 5FIT AP2 0.001025 0.42669 6.12245
305 2YD6 FLC 0.00008988 0.54523 6.13208
306 4EXO PYR 0.001076 0.4553 6.16438
307 1H9G COA MYR 0.00381 0.42531 6.17284
308 1Y9Q MED 0.008536 0.40135 6.25
309 2WEI VGG 0.01104 0.4081 6.27178
310 2YCJ C2F 0.002534 0.41386 6.27306
311 1Y2W NAG 0.00903 0.40031 6.33803
312 2W8Q SIN 0.0009491 0.44947 6.36364
313 1HEX NAD 0.01109 0.40729 6.36364
314 1WUR 8DG 0.008364 0.40494 6.36364
315 3P0K FAD 0.001252 0.43863 6.39098
316 4BCS BTN 0.002689 0.41515 6.4
317 2WCV FUC 0.002822 0.40431 6.42857
318 1TU3 GNP 0.003725 0.42421 6.43275
319 1XDN ATP 0.000002706 0.5309 6.4982
320 3S2Y FMN 0.004953 0.40877 6.53266
321 4JCA CIT 0.02142 0.40911 6.58683
322 2YVF FAD 0.00231 0.46633 6.66667
323 2YVF NAD 0.002395 0.46633 6.66667
324 1BGQ RDC 0.002051 0.43654 6.66667
325 4A6F SEP 0.02165 0.40888 6.66667
326 3W2W ATP 0.001028 0.4039 6.66667
327 1I0Z OXM 0.02069 0.40264 6.66667
328 1JUV NDP 0.001135 0.44724 6.73575
329 2DTJ THR 0.000955 0.41449 6.74157
330 3K56 IS3 0.003503 0.40836 6.76692
331 3OZG SSI 0.0005739 0.44162 6.8
332 4Q3F TLA 0.002689 0.4134 6.83761
333 3R51 MMA 0.01349 0.41162 6.875
334 1XX4 BAM 0.006687 0.4263 6.89655
335 1PR9 NAP 0.0002092 0.48734 6.96721
336 3D3W NAP 0.0003111 0.47707 6.96721
337 4O8A 2OP 0.002131 0.45016 6.9697
338 2EFJ 37T 0.00216 0.40216 6.9697
339 1YAG ATP 0.002518 0.42799 7.27273
340 1VBH PEP 0.0003228 0.42621 7.27273
341 4KCT PYR 0.001435 0.4155 7.27273
342 3O03 NAP 0.01449 0.40105 7.27273
343 1SC3 MLI 0.003979 0.42919 7.30337
344 3T2W BTN 0.0009667 0.41324 7.37705
345 1NZY BCA 0.006702 0.41648 7.43494
346 4BMO FMN 0.00165 0.43889 7.56302
347 3DLS ADP 0.0002734 0.48617 7.57576
348 1YS4 NAP 0.003773 0.41907 7.57576
349 3S9K CIT 0.001997 0.48232 7.62712
350 1SS4 CIT 0.000008523 0.65196 7.84314
351 1SS4 GSH 0.01005 0.43842 7.84314
352 2Q1A 2KT 0.007608 0.40348 7.84983
353 4IJP 1EH 0.01589 0.40801 7.87879
354 1VR0 3SL 0.001204 0.4184 8.09717
355 2XI7 XI7 0.0003884 0.50949 8.15217
356 2J8Z NAP 0.01426 0.40398 8.18182
357 1CL2 PPG 0.008438 0.40133 8.18182
358 4RJK PYR 0.01662 0.40056 8.18182
359 2EB5 OXL 0.0007528 0.44612 8.2397
360 3WVR AMP 0.01245 0.40556 8.2774
361 3KJQ B94 0.0002524 0.42567 8.42105
362 3FS8 ACO 0.0398 0.41911 8.48485
363 3FS8 TDR 0.03346 0.41911 8.48485
364 4C2G ALA ALA ALA ALA 0.002575 0.40583 8.48485
365 1L1Q 9DA 0.001332 0.43368 8.60215
366 3C1O NAP 0.001183 0.4432 8.72274
367 1C1L GAL BGC 0.003317 0.42549 8.75912
368 4BCQ TJF 0.005354 0.41598 8.77863
369 2IUW AKG 0.003 0.40329 8.82353
370 4INB 1F6 0.007746 0.40283 8.90411
371 2FR6 URI 0.0002322 0.40219 8.90411
372 1HFA PIO 0.001764 0.48712 8.99654
373 1JAC AMG 0.01221 0.42147 9.02256
374 3IOI 1GW 0.004992 0.42714 9.0604
375 3L24 GOA 0.0005244 0.47937 9.09091
376 3QV9 QV7 0.006676 0.40021 9.09091
377 1ECM TSA 0.001354 0.41646 9.17431
378 4P3H 25G 0.03134 0.40417 9.32642
379 3H86 AP5 0.01527 0.42406 9.375
380 3PTG 932 0.006179 0.41301 9.39394
381 1VJT NAD 0.006113 0.40699 9.39394
382 2Y6P CTP 0.0014 0.40762 9.40171
383 1B74 DGN 0.006636 0.41897 9.44882
384 2X2M X2M 0.01158 0.4166 9.55414
385 4F8L GAL 0.01985 0.41904 9.65517
386 2VQ5 HBA 0.005364 0.41628 9.95025
387 2VQ5 LDP 0.01291 0.41253 9.95025
388 2Q8H TF4 0.003894 0.43759 10
389 3GM5 CIT 0.001642 0.43176 10.0629
390 4HZO COA 0.001094 0.42595 10.0629
391 4PLG OXM 0.007123 0.4262 10.303
392 4PLG NAI 0.007123 0.4262 10.303
393 2NLI FMN 0.01611 0.42115 10.303
394 2NLI LAC 0.01611 0.42115 10.303
395 2C31 ADP 0.03022 0.41991 10.303
396 2C31 TZD 0.03735 0.41606 10.303
397 1OGZ EQU 0.0006421 0.43457 10.4
398 2X2T GAL NGA 0.001985 0.45164 10.4575
399 4LFL TG6 0.001191 0.41134 10.4651
400 1R27 MGD 0.003497 0.43853 10.6061
401 2P1M IHP 0.0009976 0.44795 10.625
402 2QQF A1R 0.00218 0.43387 10.7143
403 1XOC VAL ASP SER LYS ASN THR SER SER TRP 0.005135 0.43549 10.9091
404 3CQD ATP 0.005915 0.42971 11.0032
405 1EDO NAP 0.0004076 0.50627 11.0656
406 1C4U IH1 0.004034 0.41333 11.1111
407 4EKV BTN 0.006425 0.42366 11.3208
408 1T0S BML 0.001049 0.4558 11.6279
409 2FOI JPA 0.000926 0.41497 11.6667
410 3N5O GSH 0.003225 0.41624 11.9149
411 3RF4 FUN 0.002213 0.41388 12.069
412 3I6B KDO 0.004483 0.40178 12.2222
413 4GQB 0XU 0.006776 0.43974 12.4242
414 2F01 BTQ 0.01847 0.42715 12.5984
415 2F01 BTN 0.02204 0.42356 12.5984
416 3AHC TPP 0.00117 0.45124 12.7273
417 3VKX T3 0.002893 0.42105 13.0268
418 3CEV ARG 0.001554 0.41419 13.0435
419 1Y1A GSH 0.002924 0.46401 13.1148
420 3TA2 AKG 0.009684 0.41109 13.5593
421 4C2V YJA 0.01519 0.42082 13.6364
422 4G28 0W8 0.002664 0.40526 14.094
423 4CCN OGA 0.0009031 0.44277 14.2857
424 2X61 NGA GAL SIA 0.0203 0.42083 14.3411
425 2X61 CH 0.02503 0.40422 14.3411
426 1H8G CHT 0.01796 0.42137 15.7895
427 1NME 159 0.004737 0.40322 16.4384
428 2XBP ATP 0.01094 0.42593 16.8142
429 1H2K OGA 0.006584 0.40615 17.0732
430 1XE7 GUN 0.009589 0.41876 18.2266
431 2PNZ UDP 0.00843 0.40946 19.2771
432 2DVZ GLU 0.00186 0.40292 19.4268
433 3UEC ALA ARG TPO LYS 0.002535 0.43065 19.863
434 2CFM AMP 0.000002305 0.56037 21.2121
435 1NU4 MLA 0.006758 0.44391 22.6804
436 4CCO OGA 0.001251 0.42364 25
437 3SJ0 DXC 0.006251 0.41334 25.3521
438 2BOI MFU 0.001676 0.41864 30.9735
439 3BU5 ATP 0.01401 0.40708 33.3333
Pocket No.: 2; Query (leader) PDB : 1CKN; Ligand: GTP; Similar sites found: 16
This union binding pocket(no: 2) in the query (biounit: 1ckn.bio3) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3F7Z 34O 0.01425 0.40672 1.81818
2 4CC6 L5Y 0.0000231 0.52833 2.83019
3 5TT6 ATP 0.00006747 0.43567 3.0303
4 1RE8 BD2 0.01145 0.44206 3.63636
5 3PE2 E1B 0.0178 0.4317 3.63636
6 2XMY CDK 0.005591 0.47145 3.69128
7 5C4L 4XR 0.01192 0.42755 3.73832
8 5JKG 6LF 0.01284 0.43269 4.18006
9 5GZ9 ANP 0.01718 0.40959 4.2623
10 4USF 6UI 0.02798 0.40034 4.60526
11 5H2D ERG 0.02428 0.40197 4.84848
12 5COU ATP 0.000005895 0.57017 6.06061
13 5DZT AMP 0.008781 0.41178 6.06061
14 4YZC STU 0.02474 0.41653 6.9697
15 5AWM ANP 0.003817 0.41649 7.27273
16 3OFM 4B0 0.009184 0.40974 9.09091
Pocket No.: 3; Query (leader) PDB : 1CKN; Ligand: GTP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1ckn.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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