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Receptor
PDB id Resolution Class Description Source Keywords
1B66 1.9 Å EC: 4.6.1.10 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE RATTUS RATTUS TETRAHYDROBIOPTERIN BIOSYNTHESIS PHOSPHATE ELIMINATION PTESYNTHESIS
Ref.: CRYSTALLOGRAPHIC AND KINETIC INVESTIGATIONS ON THE OF 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE. J.MOL.BIOL. V. 286 851 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BIO A:700;
B:701;
Valid;
Valid;
none;
none;
submit data
237.215 C9 H11 N5 O3 C[C@H...
ZN A:401;
B:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1B66 1.9 Å EC: 4.6.1.10 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE RATTUS RATTUS TETRAHYDROBIOPTERIN BIOSYNTHESIS PHOSPHATE ELIMINATION PTESYNTHESIS
Ref.: CRYSTALLOGRAPHIC AND KINETIC INVESTIGATIONS ON THE OF 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE. J.MOL.BIOL. V. 286 851 1999
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1B66 - BIO C9 H11 N5 O3 C[C@H]([C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1B66 - BIO C9 H11 N5 O3 C[C@H]([C@....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4NTK - ZSP C9 H11 N5 O3 C/C(=C(C1=....
2 1B66 - BIO C9 H11 N5 O3 C[C@H]([C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BIO; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 BIO 1 1
2 NEO 0.701754 0.830508
3 NEU 0.701754 0.830508
4 MPU 0.701754 0.830508
5 HHR 0.483333 0.818182
6 HHS 0.47541 0.884615
7 PMM 0.432836 0.707692
8 HH2 0.408451 0.686567
9 PE0 0.403509 0.82
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 1b66.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1YQC GLV 4.28571
2 2WMC MGP 12.1429
3 2A0S BIO 29.2857
4 1Y13 BIO 29.2857
Pocket No.: 2; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1b66.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1b66.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1b66.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1b66.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1b66.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1b66.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1b66.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 1b66.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 1b66.bio1) has 1 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 1b66.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 1B66; Ligand: BIO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 1b66.bio1) has 1 residues
No: Leader PDB Ligand Sequence Similarity
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