CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 IN COMPLEXED WITH INHIBITOR
PDB id Source Resolution
1Q5K HOMO SAPIENS 1.94 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
TMU Valid Ki =  38.0 nM   launch gocavviewer-lite   308.313
C12 H12 N4 O4 S
 COc1ccc(cc1)CNC(=O)Nc2ncc(s2)[N+](=O)[O-]

STRUCTURAL INSIGHTS AND BIOLOGICAL EFFECTS OF GLYCOGEN SYNTHASE KINASE 3-SPECIFIC INHIBITOR AR-A014418. J.BIOL.CHEM. V. 278 45937 2003

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90% Homology Family

The Class containing this family consists of a total of 2 families.
Leader:    2JLD
EXTREMELY TIGHT BINDING OF RUTHENIUM COMPLEX
TO GLYCOGEN SYNTHASE KINASE 3
PDB id Binding data Representative ligand
2JLD ic50 < 0.04 nM AG1
1J1B   ANP
1J1C   ADP
1PYX   ANP
1Q3D ic50 = 15.0 nM STO
1Q3W ic50 = 4.0 nM ATU
1Q41 ic50 = 22.0 nM IXM
1Q5K Ki = 38.0 nM TMU
1R0E   DFN
3DU8 ic50 = 0.146 uM 553
3I4B Ki = 7.0 nM Z48