KINASE DOMAIN OF CSRC IN COMPLEX WITH INHIBITOR RL38 (TYPE III)
PDB id Source Resolution
3F3T 2.5 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
1AU Valid ic50 =  64.1 uM   launch gocavviewer-lite   399.488
C24 H25 N5 O
 CC(C)(C)c1cc(n(n1)c2cccc(c2)N)NC(=O)Nc3cccc4c3cccc4

A NEW SCREENING ASSAY FOR ALLOSTERIC INHIBITORS OF CSRC NAT.CHEM.BIOL. V. 5 394 2009

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90% Homology Family

The Class containing this family consists of a total of 22 families.
Leader:    3G5D
KINASE DOMAIN OF CSRC IN COMPLEX WITH DASATINIB
PDB id Binding data Representative ligand
3G5D ic50 = 4.0E-4 uM 1N1
1YOL   S03
2BDF ic50 = 0.067 uM 24A
2BDJ ic50 = 4.5E-4 uM HET
2OIQ Kd = 42.0 uM STI
3DQW   SAP
3DQX   AMP
3EL8 ic50 = 25.0 nM PD5
3EN6 ic50 = 0.235 uM KS5
3F3T ic50 = 64.1 uM 1AU
3F3U ic50 < 1.0 uM 1AW
3F6X   IHH
3G6G ic50 = 18.0 nM G6G
3G6H ic50 = 4.6 nM G6H
3GEQ   PP2