CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY (PH) DOMAIN BOUND TO INOSITOL (1,3,4,5)-TETRAKISPHOSPHATE
PDB id Source Resolution
1W1D HOMO SAPIENS 1.5 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
4IP Valid Ki =  0.3 uM   launch gocavviewer-lite   500.075
C6 H16 O18 P4
 [C@@H]1(C([C@@H]([C@H](C([C@H]1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)O)OP(=O)(O)O)O

STRUCTURAL INSIGHTS INTO THE REGULATION OF PDK1 BY PHOSPHOINOSITIDES AND INOSITOL PHOSPHATES EMBO J. V. 23 3918 2004

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90% Homology Family

The Class containing this family consists of a total of 16 families.
Leader:    1W1G
CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY
(PH) DOMAIN BOUND TO DIC4-PHOSPHATIDYLINOSITOL
(3,4,5)- T RISPHOSPHATE
PDB id Binding data Representative ligand
1W1G Ki = 0.021 uM 4PT
1W1D Ki = 0.3 uM 4IP