CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY (PH) DOMAIN BOUND TO DIC4-PHOSPHATIDYLINOSITOL (3,4,5)- T RISPHOSPHATE
PDB id Source Resolution
1W1G HOMO SAPIENS 1.45 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
4PT Valid Ki =  0.021 uM Fewer atoms than expected were found for ligand in PDB. % Diff = 0.767442  launch gocavviewer-lite   716.35
C17 H36 O22 P4
 CCC[C@@H](O)O[C@H](COC(=O)CCC)CO[P@@](=O)(O)OC1[C@@H]([C@@H](C([C@@H]([C@H]1O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)O

STRUCTURAL INSIGHTS INTO THE REGULATION OF PDK1 BY PHOSPHOINOSITIDES AND INOSITOL PHOSPHATES EMBO J. V. 23 3918 2004

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90% Homology Family

The Class containing this family consists of a total of 16 families.
Leader:    1W1G
CRYSTAL STRUCTURE OF THE PDK1 PLECKSTRIN HOMOLOGY
(PH) DOMAIN BOUND TO DIC4-PHOSPHATIDYLINOSITOL
(3,4,5)- T RISPHOSPHATE
PDB id Binding data Representative ligand
1W1G Ki = 0.021 uM 4PT
1W1D Ki = 0.3 uM 4IP