FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT
PDB id Source Resolution
1QL9 RATTUS NORVEGICUS 2.3 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
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Viewer		 Molecular
Weight
(Da)		 Formula SMILES
ZEN Valid Ki =  4.45 uM   launch gocavviewer-lite   499.025
C25 H27 Cl N4 O3 S
 c1cc(cc2c1cc(cc2)Cl)S(=O)(=O)N3CCN(CC3)C(=O)C4CCN(CC4)c5ccncc5
SO4 Invalid            

RECONSTRUCTING THE BINDING SITE OF FACTOR XA IN TRYPSIN REVEALS LIGAND-INDUCED STRUCTURAL PLASTICITY J.MOL.BIOL. V. 325 963 2003

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90% Homology Family

The Class containing this family consists of a total of 12 families.
Leader:    1J17
FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH
RAT TRYPSIN MUTANT X99/175/190RT
PDB id Binding data Representative ligand
1J17 Ki = 6.05 uM ZEN
1ANC   BEN
1AND   BEN
1ANE   BEN
1BRA Ki = 15000.0 uM BEN
1DPO   BDN
1J14 Ki = 32.2 uM BEN
1J15 Ki = 143.0 uM BEN
1J16 Ki = 143.0 uM BEN
1QL9 Ki = 4.45 uM ZEN
1TRM   BEN