FACTOR INHIBITING HIF-1 ALPHA WITH N,3-DIHYDROXYBENZAMIDE
PDB id Source Resolution
2WA4 2.5 angstroms
Ligand Information
Ligand Validity Binding
Data		 Ligand
Warnings		 Eolus Viewer
(click picture
to launch)		 Chemaxon
Viewer		 Molecular
Weight
(Da)		 Formula SMILES
SO4 Invalid            
069 Valid ic50 =  18.0 uM   launch gocavviewer-lite   153.135
C7 H7 N O3
 c1cc(cc(c1)O)C(=O)NO

STRUCTURAL BASIS FOR BINDING OF CYCLIC 2-OXOGLUTARATE ANALOGUES TO FACTOR-INHIBITING HYPOXIA-INDUCIBLE FACTOR. BIOORG.MED.CHEM.LETT. V. 20 6125 2010

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90% Homology Family

The Class containing this family consists of a total of 7 families.
Leader:    2WA4
FACTOR INHIBITING HIF-1 ALPHA WITH N,3-DIHYDROXYBENZAMIDE
PDB id Binding data Representative ligand
2WA4 ic50 = 18.0 uM 069
1MZE   TAR
1MZF   AKG
2CGN   SIN
2W0X ic50 = 625.0 uM PD2
2WA3 ic50 = 1.0 mM A29
2YC0 ic50 = 1500.0 uM 2HG
2YDE ic50 = 189.0 uM S2G