 
PDB ID
|
Resolution
|
Source
|
Class
|
Ligands
|
Binding Data
|
Molecular Weight (Da)
|
|---|---|---|---|---|---|---|
| 4C7I | 1.3 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | JJ1, MG, DMS, MYA | 512.726, 24.305, 78.133, 977.89 | |
| 4CGO | 1.3 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, 6KV | ic50 = 0.299 uM | 977.89, 24.305, 344.478 |
| 5A27 | 1.37 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, TUT, MYA | Ki = 0.02 uM | 24.305, 401.887, 977.89 |
| 4C7H | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | EN5, ENF, COA, MG, DMS, MYA | 511.741, 722.096, 767.534, 24.305, 78.133, 977.89 | |
| 4CGP | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, MYA | 24.305, 977.89 | |
| 4CYN | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, A6M, MYA | Ki = 1406 nM | 24.305, 407.333, 977.89 |
| 6QDB | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWQ | 977.89, 24.305, 330.451 | |
| 6QDC | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HXE | ic50 = 0.62 uM | 977.89, 24.305, 358.504 |
| 6QDE | 1.45 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWW | 977.89, 24.305, 388.573 | |
| 6QDH | 1.45 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | HXQ, MYA, HZ5, HZ8, MG | 500.66, 977.89, 203.262, 313.44, 24.305 | |
| 6QD9 | 1.46 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWT | ic50 = 2.7 uM | 977.89, 24.305, 332.467 |
| 4CGL | 1.48 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, MYA, A6K | ic50 = 0.031 uM | 24.305, 977.89, 407.333 |
| 5A28 | 1.48 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | TUQ, MG, MYA | Ki = 0.01 uM | 401.89, 24.305, 977.89 |
| 6QDF | 1.49 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWN | ic50 = 1.2 uM | 977.89, 24.305, 388.573 |
| 2R8Q | 1.5 | LEISHMANIA MAJOR | ENZYME 3.1.4.17 | IBM, ZN, MG | ic50 = 580 uM | 222.244, 65.409, 24.305 |
| 4A30 | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | QMI, MYA, GOL, CL | 413.118, 977.89, 92.094, 35.453 | |
| 4CYO | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, UEK, MYA | Ki = 1.6 nM | 24.305, 558.471, 977.89 |
| 4UCP | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | 9X3, MYA | Kd = 200 uM | 220.311, 977.89 |
| 5G21 | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, YN4, MYA | 24.305, 477.579, 977.89 | |
| 6EU5 | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | BXN, MYA | Ki = 2 nM | 514.511, 977.89 |
| 5G20 | 1.52 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | DMS, QBY, MG, MYA | 78.133, 408.513, 24.305, 977.89 | |
| 6EWF | 1.54 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | 31A, MYA | 367.442, 977.89 | |
| 6GNU | 1.54 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, F5Z | 977.89, 493.704 | |
| 4CYP | 1.55 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, A62, MYA | 24.305, 408.318, 977.89 | |
| 4EF8 | 1.56 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, GOL, FMN, 0FI | 96.063, 92.094, 456.344, 137.202 | |
| 6MSN | 1.59 | LEISHMANIA MAJOR | ENZYME 4.2.1.2 | JYD, SF4 | Ki = 8.9 uM | 150.153, 351.64 |
| 2WSA | 1.6 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, 646 | Kd = 1 nM | 977.89, 495.425 |
| 4EF9 | 1.6 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, GOL, FMN, 4NF | 96.063, 92.094, 456.344, 182.2 | |
| 6GNT | 1.6 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, F5Q, GOL | 977.89, 506.703, 92.094 | |
| 6QDA | 1.6 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWZ | ic50 = 0.24 uM | 977.89, 24.305, 338.45 |
| 4CYQ | 1.65 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, YAU, MYA | Ki = 59 nM | 24.305, 559.456, 977.89 |
| 6QDD | 1.65 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | HXW, MYA, MG, DMS | 368.499, 977.89, 24.305, 78.133 | |
| 4CGN | 1.69 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | 7AH, MG, MYA | ic50 = 0.55 uM | 351.417, 24.305, 977.89 |
| 1Y63 | 1.7 | LEISHMANIA MAJOR | NON-ENZYME OTHER | NA, MN, BR, ADP | 22.99, 54.938, 79.904, 427.201 | |
| 4CGM | 1.7 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, CWZ, MYA | ic50 = 1.02 uM | 24.305, 440.603, 977.89 |
| 1E7W | 1.75 | LEISHMANIA MAJOR | ENZYME 1.5.1.33 | NDP, MTX, EDO | 745.421, 454.439, 62.068 | |
| 4JZX | 1.8 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | 476, IPE, CA | Kd = 198.6 nM | 324.227, 246.092, 40.078 |
| 4UCN | 1.8 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | JRB, MYA | 177.246, 977.89 | |
| 6GNS | 1.8 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | F65, MYA | 541.745, 977.89 | |
| 6VJC | 1.8 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | PEG, ACT, IPR, 476, CA | 106.12, 59.044, 248.108, 324.227, 40.078 | |
| 3MHU | 1.85 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | EJZ, SO4, GOL, FMN | Ki = 212.93 uM | 201.094, 96.063, 92.094, 456.344 |
| 2YAY | 1.86 | LEISHMANIA MAJOR | ENZYME 3.6.1.23 | DUP, CA | Kd = 0.8 uM | 467.157, 40.078 |
| 6GNH | 1.89 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | F4T, MYA | 418.507, 977.89 | |
| 3TQ0 | 1.9 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, NI, GOL, FUM, FMN | 96.063, 58.693, 92.094, 116.072, 456.344 | |
| 4JZB | 1.9 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | IPE, NA, CA, P2H | Kd = 342.5 nM | 246.092, 22.99, 40.078, 360.216 |
| 1XTP | 1.94 | LEISHMANIA MAJOR | ENZYME TRANSFERASES | SAI | 431.306 | |
| 6SWX | 1.95 | LEISHMANIA MAJOR | ENZYME 6.1.1.10 | LWN | ic50 = 2.06 uM | 348.307 |
| 3MJY | 1.96 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, IJZ, GOL, FMN | Ki = 82.8 uM | 96.063, 171.111, 92.094, 456.344 |
| 6QDG | 1.98 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HXN | 977.89, 24.305, 405.335 | |
| 5AG4 | 1.99 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, N8N | 977.89, 290.768 |
