 
PDB ID
|
Resolution
|
Source
|
Class
|
Ligands
|
Binding Data
|
Molecular Weight (Da)
|
|---|---|---|---|---|---|---|
| 2WSA | 1.6 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, 646 | Kd = 1 nM | 977.89, 495.425 |
| 4CYO | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, UEK, MYA | Ki = 1.6 nM | 24.305, 558.471, 977.89 |
| 6EU5 | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, BXN | Ki = 2 nM | 977.89, 514.511 |
| 5A28 | 1.48 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | TUQ, MG, MYA | Ki = 0.01 uM | 401.89, 24.305, 977.89 |
| 5A27 | 1.37 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, TUT, MYA | Ki = 0.02 uM | 24.305, 401.887, 977.89 |
| 4CGL | 1.48 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, MYA, A6K | ic50 = 0.031 uM | 24.305, 977.89, 407.333 |
| 4CYQ | 1.65 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, YAU, MYA | Ki = 59 nM | 24.305, 559.456, 977.89 |
| 3H4V | 2.4 | LEISHMANIA MAJOR | ENZYME 1.5.1.33 | NAP, DVP | Ki = 0.1 uM | 743.405, 436.467 |
| 4K10 | 2.3 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | MG, MES, NI9, NA, PEG, ACT | Kd = 119.5 nM | 24.305, 195.237, 302.111, 22.99, 106.12, 59.044 |
| 4JZX | 1.8 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | 476, IPE, CA | Kd = 198.6 nM | 324.227, 246.092, 40.078 |
| 6QDA | 1.6 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWZ | ic50 = 0.24 uM | 977.89, 24.305, 338.45 |
| 4CGO | 1.3 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, 6KV | ic50 = 0.299 uM | 977.89, 24.305, 344.478 |
| 4JZB | 1.9 | LEISHMANIA MAJOR | ENZYME 2.5.1.1 | IPE, NA, CA, P2H | Kd = 342.5 nM | 246.092, 22.99, 40.078, 360.216 |
| 4CGN | 1.69 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, 7AH, MG | ic50 = 0.55 uM | 977.89, 351.417, 24.305 |
| 6QDC | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HXE | ic50 = 0.62 uM | 977.89, 24.305, 358.504 |
| 2YAY | 1.86 | LEISHMANIA MAJOR | ENZYME 3.6.1.23 | DUP, CA | Kd = 0.8 uM | 467.157, 40.078 |
| 4CGM | 1.7 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, CWZ, MYA | ic50 = 1.02 uM | 24.305, 440.603, 977.89 |
| 4UXH | 2.4 | LEISHMANIA MAJOR | ENZYME 2.7.1.21 | T5A, ZN | ic50 = 1.1 uM | 891.354, 65.409 |
| 6QDF | 1.49 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWN | ic50 = 1.2 uM | 977.89, 24.305, 388.573 |
| 4CYN | 1.4 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MG, A6M, MYA | Ki = 1406 nM | 24.305, 407.333, 977.89 |
| 6SWX | 1.95 | LEISHMANIA MAJOR | ENZYME 6.1.1.10 | LWN | ic50 = 2.06 uM | 348.307 |
| 6QD9 | 1.46 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | MYA, MG, HWT | ic50 = 2.7 uM | 977.89, 24.305, 332.467 |
| 6MSO | 2.05 | LEISHMANIA MAJOR | ENZYME 4.2.1.2 | JYD, SF4, 1PE, GOL | Ki = 3 uM | 150.153, 351.64, 238.278, 92.094 |
| 2YAZ | 2.4 | LEISHMANIA MAJOR | ENZYME 3.6.1.23 | UMP, SO4, MG | Kd = 7.3 uM | 308.182, 96.063, 24.305 |
| 6MSN | 1.59 | LEISHMANIA MAJOR | ENZYME 4.2.1.2 | JYD, SF4 | Ki = 8.9 uM | 150.153, 351.64 |
| 5L4N | 2.35 | LEISHMANIA MAJOR | ENZYME 1.5.1.33 | PEG, 6QT, EDO, GOL, ACT, PGE, NDP | ic50 = 57 uM | 106.12, 256.253, 62.068, 92.094, 59.044, 150.173, 745.421 |
| 3MJY | 1.96 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, IJZ, GOL, FMN | Ki = 82.8 uM | 96.063, 171.111, 92.094, 456.344 |
| 2YB0 | 2.28 | LEISHMANIA MAJOR | ENZYME 3.6.1.23 | SO4, DUR | Kd = 140 uM | 96.063, 228.202 |
| 4UCM | 2.32 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | X6W, MYA | Kd = 180 uM | 201.268, 977.89 |
| 4UCP | 1.5 | LEISHMANIA MAJOR | ENZYME 2.3.1.97 | 9X3, MYA | Kd = 200 uM | 220.311, 977.89 |
| 3MHU | 1.85 | LEISHMANIA MAJOR | ENZYME 1.3.3.1 | SO4, GOL, FMN, EJZ | Ki = 212.93 uM | 96.063, 92.094, 456.344, 201.094 |
| 2R8Q | 1.5 | LEISHMANIA MAJOR | ENZYME 3.1.4.17 | ZN, MG, IBM | ic50 = 580 uM | 65.409, 24.305, 222.244 |
| 5L2R | 2.05 | LEISHMANIA MAJOR | ENZYME 4.2.1.2 | PEG, SF4, GOL, MLA, LMR | ic50 = 9.8 mM | 106.12, 351.64, 92.094, 104.061, 134.087 |
