Receptor
PDB id Resolution Class Description Source Keywords
2FF4 1.9 Å NON-ENZYME: OTHER MYCOBACTERIUM TUBERCULOSIS EMBR IN COMPLEX WITH LOW AFFINITY PHOSPHOPEPTIDE MYCOBACTERIUM TUBERCULOSIS WINGED-HELIX; TETRATRICOPEPTIDE REPEAT; BETA-SANDWICH TRANS
Ref.: MOLECULAR STRUCTURE OF EMBR, A RESPONSE ELEMENT OF KINASE SIGNALING IN MYCOBACTERIUM TUBERCULOSIS. PROC.NATL.ACAD.SCI.USA V. 103 2558 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SER LEU GLU VAL TPO GLU ALA ASP THR E:1;
F:3;
 Valid;
Valid;
 none;
none;
 Kd = 185 uM
823.727 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FF4 1.9 Å NON-ENZYME: OTHER MYCOBACTERIUM TUBERCULOSIS EMBR IN COMPLEX WITH LOW AFFINITY PHOSPHOPEPTIDE MYCOBACTERIUM TUBERCULOSIS WINGED-HELIX; TETRATRICOPEPTIDE REPEAT; BETA-SANDWICH TRANS
Ref.: MOLECULAR STRUCTURE OF EMBR, A RESPONSE ELEMENT OF KINASE SIGNALING IN MYCOBACTERIUM TUBERCULOSIS. PROC.NATL.ACAD.SCI.USA V. 103 2558 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 2FF4 Kd = 185 uM SER LEU GLU VAL TPO GLU ALA ASP THR n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 2FF4 Kd = 185 uM SER LEU GLU VAL TPO GLU ALA ASP THR n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 2FF4 Kd = 185 uM SER LEU GLU VAL TPO GLU ALA ASP THR n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SER LEU GLU VAL TPO GLU ALA ASP THR; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 SER LEU GLU VAL TPO GLU ALA ASP THR 1 1
2 SER LEU LEU LYS LYS LEU LEU ASP 0.471698 0.77193
3 SER LEU LYS ILE ASP ASN GLU ASP 0.456693 0.745763
4 TYR ALA GLY SEP TPO ASP GLU ASN 0.453901 0.83871
5 SER ALA LYS ILE ASP ASN LEU ASP 0.415385 0.745763
6 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.41358 0.72973
7 SER LEU LYS ILE ASP ASN LEU ASP 0.409449 0.745763
8 SER GLN LEU LYS ASN ASN ALA LYS GLU ILE 0.407692 0.733333
Similar Ligands (3D)
Ligand no: 1; Ligand: SER LEU GLU VAL TPO GLU ALA ASP THR; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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